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Perioperative Analgesic Effects of PENG Versus PENG Plus LFCN Block in Hip Surgeries

Comparison of Postoperative Analgesic Efficacy of Preoperative Pericapsular Nerve Group (PENG) Block With PENG Block and Lateral Femoral Cutaneous Nerve Block in Lateral Incision Hip Surgery

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07329829
Enrollment
72
Registered
2026-01-09
Start date
2025-11-01
Completion date
2026-07-01
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia, Postoperative, HİP FRACTURE, Hip Surgery (Lateral Incision), Postoperative Pain Management, Regional Anesthesia Success

Keywords

Pericapsular Nerve Group Block (PENG Block), Lateral Femoral Cutaneous Nerve Block (LFCN Block), Hip Surgery, Regional Anesthesia, Postoperative Analgesia, Pain Control, Opioid Consumption, Early Mobilization

Brief summary

This study is designed to find the best way to control pain after hip surgery performed through a side (lateral) incision. Two different types of nerve blocks used before the operation will be compared. In one group, patients will receive a Pericapsular Nerve Group (PENG) block, which numbs the main nerves that carry pain signals from the hip joint. In the other group, patients will receive a PENG block together with a Lateral Femoral Cutaneous Nerve (LFCN) block, which adds extra pain relief for the skin and outer part of the thigh. A total of 72 patients between 18 and 80 years old will take part in this study. All operations will be done under spinal anesthesia. Pain levels will be measured several times during the first 24 hours after surgery using a simple 0-10 pain scale. Patients will receive pain medicine through a pump that allows them to press a button when they feel pain. The total amount of medicine used will be recorded. The researchers will also monitor when patients first need pain medicine, when they can start walking, how satisfied they are with pain control, and if they experience side effects such as nausea or dizziness. By comparing the two methods, the study aims to see whether adding the LFCN block to the PENG block provides better pain control, lower drug use, faster recovery, and higher patient comfort after hip surgery.

Detailed description

Postoperative pain following hip surgery remains a significant clinical challenge, particularly in procedures performed through a lateral incision, where both deep articular and superficial cutaneous pain components contribute to patient discomfort. Effective regional anesthesia techniques are essential to optimize postoperative analgesia, facilitate early mobilization, and reduce opioid-related adverse effects. The Pericapsular Nerve Group (PENG) block has been introduced as a motor-sparing regional anesthesia technique targeting the articular branches of the femoral, obturator, and accessory obturator nerves, providing effective analgesia for hip joint-related pain. However, due to its limited coverage of cutaneous innervation, patients undergoing lateral incision hip surgery may continue to experience residual superficial pain. The Lateral Femoral Cutaneous Nerve (LFCN) block selectively targets the sensory innervation of the anterolateral thigh and may complement the PENG block by addressing the cutaneous component of postoperative pain. The combined use of PENG and LFCN blocks has the potential to provide more comprehensive analgesia without compromising motor function. This study is designed to evaluate whether the addition of an LFCN block to a standard PENG block enhances postoperative pain control and recovery outcomes in patients undergoing hip surgery via a lateral approach. By comparing these two regional anesthesia strategies, the study aims to contribute evidence-based guidance for optimizing multimodal analgesia protocols in hip surgery.

Interventions

PROCEDUREPericapsular nerve group (PENG) block

An ultrasound-guided Pericapsular Nerve Group (PENG) block will be performed preoperatively using standard local anesthetic techniques to provide postoperative analgesia in patients undergoing lateral incision hip surgery.

PROCEDURELateral Femoral Cutaneous Nerve (LFCN) Block

An ultrasound-guided Lateral Femoral Cutaneous Nerve (LFCN) block will be performed preoperatively as an adjunct to the PENG block to enhance postoperative analgesia in patients undergoing lateral incision hip surgery.

Sponsors

Başakşehir Çam & Sakura City Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients aged between 18 and 80 years * Patients scheduled for elective or trauma-related hip surgery performed through a lateral incision under spinal anesthesia * Patients receiving a preoperative ultrasound-guided Pericapsular Nerve Group (PENG) block or a PENG block combined with a Lateral Femoral Cutaneous Nerve (LFCN) block * American Society of Anesthesiologists (ASA) physical status I-III * Patients with full orientation and the ability to cooperate * Ability to understand the study procedures and provide written informed consent

Exclusion criteria

* Contraindications to regional anesthesia, including coagulopathy or local infection at the injection site * Presence of neuropathic disorders or conditions that may affect pain perception, including chronic analgesic use * Requirement for conversion to general anesthesia * Postoperative admission to the intensive care unit * Known allergy or hypersensitivity to opioids or local anesthetics * American Society of Anesthesiologists (ASA) physical status IV-V

Design outcomes

Primary

MeasureTime frameDescription
Postoperative Pain Intensity (NRS Score)2, 6, 12, and 24 hours postoperativelyPostoperative pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst imaginable pain), both at rest and during movement.

Secondary

MeasureTime frameDescription
Total Postoperative Opioid ConsumptionFirst 24 hours postoperativelyTotal opioid consumption during the first 24 hours postoperatively will be recorded using a patient-controlled analgesia (PCA) device and converted to morphine equivalent dose (mg).
Patient Satisfaction ScoreWithin the first 24 hours postoperativelyPatient satisfaction with postoperative pain management will be assessed using a 5-point Likert Satisfaction Scale, ranging from 1 (very dissatisfied) to 5 (very satisfied), where higher scores indicate greater patient satisfaction.
Time to First MobilizationWithin the first 24 hours postoperativelyTime to first mobilization after surgery will be recorded in hours.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026