Morbid Obesity Requiring Bariatric Surgery
Conditions
Keywords
morbid obesity, serum apolipoproteins, apolipoprotein AI, apolipoprotein AII, apolipoprotein B100, apolipoprotein CII, apolipoprotein CIII, apolipoprotein D, apolipoprotein E, apolipoprotein E4, apolipoprotein H, apolipoprotein J, apolipoprotein M, sleeve gastrectomy, bariatric surgery
Brief summary
The study looks at whether a specific protein in the blood, called apolipoprotein, can predict how much weight a person might lose after sleeve gastrectomy, a surgery for people with severe obesity. We want to find a specific level of this protein that shows which patients are most likely to lose weight successfully after surgery. By identifying this level, we hope to guide doctors in deciding who should have the surgery and who might do better with non-surgical weight loss methods.
Detailed description
The subject of our research is whether serum apolipoprotein levels can be a predictive value for weight loss in patients who will undergo sleeve gastrectomy due to morbid obesity. Our aim is to determine a cut-off value for patients who benefit most from bariatric surgery based on preoperative serum apolipoprotein levels. By including this value among the surgical indications, we plan to direct patients less likely to benefit from surgery to conservative approaches.
Interventions
Laparoscopic Sleeve Gastrectomy
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients aged 18 to 75 * International Classification of Diseases (ICD) code E66 diagnosis (obesity) * Patients who have given consent for sleeve gastrectomy * Patients who are suitable for general anesthesia
Exclusion criteria
* Patients who did not give consent to be included in the study * Patients who are scheduled for surgery other than sleeve gastrectomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in body mass index at 8 months | 8 months after surgery |
Secondary
| Measure | Time frame |
|---|---|
| Change in lipid profile at 8 months | 8 months after surgery |
Countries
Turkey (Türkiye)