Brain Tumor
Conditions
Keywords
radiotherapy, brain tumor, mask, surface guidance
Brief summary
The aim of this study is to investigate the technical feasibility of brain radiotherapy without immobilization masks using surface imaging to ensure accurate patient positioning and continuous motion monitoring.
Detailed description
In brain radiotherapy, immobilization using a thermoplastic mask is a standard practice to ensure treatment accuracy. However, this method causes discomfort and anxiety for patients. The development of surface imaging (Surface Guided Radiation Therapy, SGRT) could offer a solution to this problem. SGRT is a non-invasive and non-ionizing imaging technique that uses cameras to capture the patient's position in real-time. In mask-free treatment, the radiation beam can be interrupted when motion exceeds a certain threshold and restarts only when the position is corrected. Nowadays, very few studies have examined the concept of radiation therapy without immobilization masks using SGRT. As part of this study, participants will take part in a simulated mask-free session. We will determine the stability of the patient's position in the absence of a mask. Participants will also complete questionnaires concerning their feelings during sessions with and without masks.
Interventions
DEVICESurface Guided Radiation Therapy without mask
Patients are positioned using SGRT based on the reference position reconstructed from the simulation scanner. They are asked to remain still during the typical duration of a conventional radiotherapy session. Patient motion is monitored by SGRT throughout the simulated session. A CBCT scan is performed before and after the session. No treatment is delivered.
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>= 18 years old * Brain tumor treated with fractionated radiotherapy * Able to read and complete a questionnaire in French
Exclusion criteria
* Inability to remain still
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stability of patient's position | Through the course of radiation therapy (up to 6 weeks) | The stability of the patient's position will be assessed: * on the basis of internal movements (of the skull) detected by scanner imaging before and after the simulated session (on-board CBCT) * on the basis of surface movements monitored by SGRT throughout the session. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient's feelings with and without the mask | Through the course of radiation therapy (up to 6 weeks) | Patients are asked to fill in a questionnaire about their feelings (comfort, anxiety, claustrophobia, isolation, pain) during radiotherapy sessions with a mask and simulated sessions without an immobilization mask. |
| Preference of treatment | Through the course of radiation therapy (up to 6 weeks) | Patients are asked to indicate whether they prefer to be treated with or without a mask. |
Countries
Belgium
Contacts
Primary ContactDario Di Perri
Outcome results
None listed