Healthy Endurance Athlet, Inactive People
Conditions
Keywords
endurance athletes, exercise timing, sleep quality
Brief summary
Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.
Interventions
OTHERAerobic Exercise
The exercise consists of running on a treadmill at 90% of maximum aerobic speed (MAS) for 30 minutes, followed by 12% increments every 5 minutes, until exhaustion (a "time-to-exhaustion" type of exercise).
Sponsors
Centre Hospitalier Universitaire de Saint Etienne
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
This is a single-center, open-label, randomized controlled trial with two parallel crossover groups: * "Active" group * "Inactive-sedentary" group
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Group "Inactive" :No regular exercise practice (inactive people that don't follow the WHO recommendations) and have sedentary behaviors * Group "Active": Regular exercise (athletes that are specialized in aerobic exercise, with more than 300 minutes per-week over 6 months and practice at regional level).
Exclusion criteria
* Have sleep disorders medically diagnosed or detected by sleep forms cutoffs (clinical insomnia by ISI, severe risk of obstructive sleep apnea by Stop-Bang, bad sleep quality by PSQI. * Have a diagnosed mental health condition requiring treatment * Have renal, respiratory, cardiovascular or neuromuscular disease medically diagnosed. * Be pregnant or breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of deep slow-wave sleep | Once a month for 3 months | Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of core temperature | Once a month for 3 months | Assessment of core temperature until the end of the sleep period will be measured using gastrointestinal telemetric pills (eCelsius, Bodycap®, France). |
| Evaluation of autonomic nervous system thermoregulation | Once a month for 3 months | Evaluation of autonomic nervous system thermoregulation through time-domain (R-R intervals in ms) |
| Complementary sleep evaluation | Once a month for 3 months | Complementary sleep evaluation through analysis of duration of N1, N2, and REM stages (in Percentage of Total Sleep Time) |
Countries
France
Contacts
CONTACTFrédéric ROCHE, PhD
PRINCIPAL_INVESTIGATORFrédéric ROCHE, PhD
Centre Hospitalier Universitaire de Saint Etienne
Outcome results
None listed