Novel Transdermal Ketoprofen Gel Formulation for Knee Osteoarthritis

Novel Transdermal Ketoprofen Gel Formulation for Knee Osteoarthritis: Comprehensive In-Vitro and Clinical Assessment

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07319728

Enrollment

Registered

2026-01-06

Start date

2025-05-10

Completion date

2026-02-28

Last updated

2026-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

knee joint osteoarthritis, Transdermal Ketoprofen Gel

Brief summary

A single blind randomized controlled clinical study

Detailed description

A single blind randomized controlled clinical study

Interventions

DRUGketoprofen

new gel formulation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient diagnosed with osteoarthritis in knee by: Full history taking Physical examination including (joint tenderness, swelling, crepitus and limitation of motion).

Exclusion criteria

* 1\. Patients with dual diagnosis 2. Patients have skin lesion or dermatologic disease in the treatment area

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale (VAS)	2 weeks
McMaster Universities Arthritis Index (WOMAC)	2 weeks

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026