Comparison of Advanced Platelet-Rich Fibrin Versus Platelet-Rich Fibrin as a Gap-filling Material
Conditions
Keywords
Immediate dental implant placement and socket healing
Brief summary
Study type: Clinical Trial Goal: The goal of this clinical trial is to learn if Advanced Platelet-Rich Fibrin (A-PRF) versus traditional Platelet-Rich Fibrin (PRF) can improve bone healing and soft tissue outcomes in patients undergoing immediate dental implant placement. Main questions it aims to answer: Does A-PRF provide greater buccal bone preservation compared to PRF after immediate implant placement? Does A-PRF improve soft tissue healing and reduce postoperative complications compared to PRF? Comparison group: Researchers will compare A-PRF to PRF as a gap-filling material in immediate implants to see if A-PRF results in better bone and soft tissue outcomes. Participants will: Undergo tooth extraction followed by immediate implant placement Receive either A-PRF or PRF as the gap-filling material in the implant site Have CBCT scans at baseline and 6 months to measure bone thickness Have clinical assessments of soft tissue healing and implant stability Attend follow-up visits at 1 week, 1 month, 3 months, and 6 months post-surgery
Interventions
PROCEDUREImmediate Dental Implant and A-PRF
Arm 1: Advanced Platelet-Rich Fibrin (A-PRF) Participants will have a tooth extracted, the socket cleaned, and A-PRF prepared from their blood placed in the socket as a gap-filling material before immediate implant placement. Follow-up visits will assess bone and soft tissue healing and implant stability.
PROCEDUREImmediate dental implant and PRF
Arm 2: Platelet-Rich Fibrin (PRF) Participants will have a tooth extracted, the socket cleaned, and traditional PRF prepared from their blood placed in the socket as a gap-filling material before immediate implant placement. Follow-up visits will assess bone and soft tissue healing and implant stability.
Sponsors
Beni-Suef University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The selected patients has a badly decayed mandibular posterior teeth which are indicated for extraction due to dental causes (periapical abscess, trauma or caries) not periodontal as diagnosed by periapical x-ray. * Healthy patients who are classified according to the American Society of Anesthesiologists (ASA)(2022) physical status classification as class I. * Patient age ≥ 20 years old. * Surgical site with sufficient for implant placement. * Sufficient interocclusal space for prosthesis. * Good oral hygiene. * Patients have thick biotype. * Patients have socket class I.
Exclusion criteria
* Active periodontal diseases and periapical lesions not chronic infections. * Patients have parafunctional * History of alcohol or drug dependency, psychological factor that might affect the surgical or prosthodontic treatment. * Smoking. * Pregnant patients. * Patients who are not willing to complete the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical evaluation | 6 month | Implant stability will be measured by resonance frequency analysis (RFA) values expressed as implant stability quotient (ISQ) unit at 6 months post-operative |
Countries
Egypt
Outcome results
None listed