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Antiplatelet Use in Dementia Subtypes

Antiplatelet Use in All-Cause Dementia and Dementia Subtypes Among Older Adults: A Population-Based Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07313137
Enrollment
683
Registered
2025-12-31
Start date
2016-12-31
Completion date
2025-03-31
Last updated
2025-12-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia, Dementia Disorder

Keywords

Antiplatelet therapy, Older adults, Dementia subtypes

Brief summary

This population-based retrospective cohort study aimed to evaluate the appropriateness of antiplatelet therapy use among older adults with all-cause dementia and across different dementia subtypes. Medical records of patients aged 65 years and older who were evaluated at a tertiary-level geriatric outpatient clinic were reviewed. Dementia subtypes were classified according to internationally accepted diagnostic criteria. Patterns of antiplatelet use were assessed in accordance with current guideline recommendations. The study sought to determine the appropriateness of antiplatelet use across dementia subtypes and to describe real-world prescribing practices in this population.

Interventions

None listed

Sponsors

Gulhane Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age 65 years and older. * Diagnosis of dementia based on internationally accepted diagnostic criteria. * Evaluation at a tertiary-level geriatric outpatient clinic.

Exclusion criteria

* Patients with incomplete or inaccessible medical records. * Individuals with missing data on antiplatelet therapy use.

Design outcomes

Primary

MeasureTime frameDescription
Appropriateness of antiplatelet therapy useAt baseline (first geriatric outpatient clinic visit)Assessment of the appropriateness of antiplatelet therapy use according to current guideline recommendations among older adults with dementia.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026