Wolfram Syndrome, Fecal Incontinence
Conditions
Brief summary
In order to clarify the mechanism of fecal incontinence in in Wolfram syndrome and to characterize its risk factors, the examiner will reviewed the files of patients followed in a Reference Center for Rare Diseases in Ophthalmology.
Interventions
retrospective analysis of data
Sponsors
Hôpital Necker-Enfants Malades
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Wolfram syndrome
Exclusion criteria
* no information concerning fecal incontinence in data records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Urinary disorders | The date at the baseline | number of patients with urinary disorder in each group according to the group |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| sleep apnea | The date the data will be analyzed at the baseline | number of patients with sleep apnea in each group according to the group |
| frequence of swallowing disroder | The data will be analyzed at baseline | number of patients with swallowing disorders in each group according to the group |
| frequence of diabetes insipidus | The data will be analyzed at baseline | number of patients with diabetes insipidus in each group according to the group |
| mutation type | The data will be analyzed at baseline | report of mutations of WFS1 in each group |
Countries
France
Contacts
Primary Contactchristophe Orssaud, MD
Outcome results
None listed