GFAP, Glial Fibrillary Acidic Protein, Neurofilament Light Chain, Vegan Diet, Vegetarian Diet
Conditions
Brief summary
This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP. The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels?
Interventions
None listed
Sponsors
Medizinische Einrichtungen der Universität Düsseldorf
Medizinische Fakultät der Universität zu Köln
Universitätsklinkum Münster - Medizinische Klinik und Poliklinik B
Salzburger Landeskliniken
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy individuals who have followed a vegan, vegetarian, or omnivorous diet for at least one consecutive year * Aged between 18 and 40 years * Provision of written informed consent
Exclusion criteria
* Diagnose neurological disorders (e.g. neurodegenerative, inflammatory, autoimmune, infectious, vascular) * Eating disorders * Excessive alcohol consumption * Pregnancy * Recent moderate to severe infection (within the past 12 weeks) , including SARS-CoV-2 * Recent trauma, injury, or surgery (within the past 12 weeks) * Significant BMI fluctuations (\>5 points) within the last year * Patients who have been using Proton pump inhibitors (PPIs) for an extended period (e.g., 1 month).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood levels of the following biomarkers: neurofilament light chain (NfL) in pg/mL, glial fibrillary acidic protein (GFAP) in pg/mL. | Once at baseline |
Countries
Austria
Contacts
Primary ContactTobias Moser, Prof.
Outcome results
None listed