Enteral Feeding Intolerance
Conditions
Keywords
Enteral feeding intolerance, Gastric antral area
Brief summary
The objective of the BOCUSE study is to demonstrate a relationship between an early ultrasound measurement of the gastric antral area and the subsequent occurrence of poor gastric tolerance.
Interventions
OTHERGastric ultrasound with measurement of the antral area
Gastric ultrasound with measurement of the antral area
Sponsors
Centre Hospitalier Saint Joseph Saint Luc de Lyon
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years * Predicted mechanical ventilation ≥ 48 hours * Initiation of enteral nutrition via nasogastric or orogastric tube for ≥ 48 hours * Free and informed consent obtained from the patient's relative or legal representative, or inclusion in an emergency situation
Exclusion criteria
* History of major gastric surgery (bypass, total gastrectomy, biliopancreatic diversion) * Enteral nutrition via nasogastric or orogastric tube \> 96 hours * Initiation of enteral nutrition before intubation * Feeding via gastrostomy, jejunostomy, or jejunal tube * Pregnancy * Prognosis considered terminal * No ultrasound window available * Legally protected adults (under curatorship, guardianship, or judicial protection) * No social security coverage * Patient under State Medical Aid (AME)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Enteral nutrition intolerance | Within 7 days following the gastric ultrasound | Presence of regurgitation and/or vomiting and/or interruption or reduction of enteral nutrition flow rates |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of VAP | From H0 until ICU discharge, up to 3 months | Occurrence of Ventilator Associated Pneumonia |
| Mortality | At ICU discharge, at 28 days, and at 3 months | Mortality at ICU discharge, at day 28, and at 3 months |
| Duration of mechanical ventilation | From H0 until ICU discharge, up to 3 months | Number of days on mechanical ventilation |
| Number of ventilator-free days | Day 28, 3 months | Number of ventilator-free days at day 28 and 3 months |
| Length of stay in the ICU | From ICU admission until ICU discharge, up to 3 months | Length of ICU stay (in days) |
Countries
France
Outcome results
None listed