Hepatocellular Carcinoma
Conditions
Brief summary
This study evaluates barriers to early detection of liver cancer.
Detailed description
PRIMARY OBJECTIVES: I. To identify individual-level social and clinical determinants of socioeconomic disparities in late stage Hepatocellular Carcinoma (HCC) burden with a prospective survey of patients with incident HCC. II. To qualitatively explore the multilevel barriers to completion of the early detection pathway for HCC in low socioeconomic status (SES) populations. OUTLINE: This is an observational study. Participants complete surveys, have their medical records reviewed, and may complete an interview on study.
Interventions
OTHERNon-Interventional Study
Non-interventional study
Sponsors
University of Southern California
National Cancer Institute (NCI)
National Institute on Minority Health and Health Disparities (NIMHD)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \* Adults (18+) * New diagnosis of HCC * Able to provide informed consent Additional criteria: * Must complete survey * Residential address in a late stage hotspot * Medicaid insurance or uninsured * English, Spanish and Chinese speakers
Exclusion criteria
* \* Residence outside of Los Angeles County * Non-HCC liver tumors * Incarcerated patients * Pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Social determinants of health | Up to 4 years | Patient social determinants of health-related needs will be measured through a health questionnaire created for the study. The patient can respond yes or no to having a lack of transportation to and from appointments. The patient is given a scale of never true, sometimes true and often true for questions regarding food insecurity. The patient can indicate that they do or do not have housing today (or choose not to answer), and they can indicate how many times they moved in the last year as 0, 1, or 2+. For the remaining questions regarding housing, paying for utilities, paying for medications, unemployment, education and child or family care, the patient can respond yes, no or choose not to answer. Responses of yes indicate the patient has a need, and no indicates that they do not have a need. |
| Barriers to completion of the early detection pathway for liver cancer | Up to 4 years | For assessment we will conduct semi-structured interviews with key stakeholders, including low-income patients with liver cancer, providers in an interconnected safety net system, and community leaders of hotspot neighborhoods. |
Countries
United States
Contacts
CONTACTKali Zhou
PRINCIPAL_INVESTIGATORKali Zhou
University of Southern California
Outcome results
None listed