Prognosis of Early-onset Anorexia Nervosa

Evalutation of the Prognosis and Quality of Life of Patients Hospitalized for Early-onset Anorexia Nervosa

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07311356

Acronym

AM2P

Enrollment

140

Registered

2025-12-30

Start date

2025-12-05

Completion date

2026-03-31

Last updated

2026-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia Nervosa

Keywords

early-onset anorexia nervosa, quality of life, prognosis

Brief summary

The AM2P study aims to evaluate the long-term prognosis and quality of life of patients with early-onset anorexia nervosa, assessed 4 to 9 years after hospitalization. Prognosis will be determined using a composite outcome measure based on questionnaire responses and health indicators, including body mass index (BMI). In addition, the study will examine the patients' overall physical condition both at the time of assessment and during the interval between their last hospitalization and the present evaluation.

Detailed description

This study includes all patients who were hospitalized at Robert Debré Hospital in Paris between 2016 and 2021 for early-onset anorexia nervosa. During follow-up interviews, participants will complete a standardized set of questionnaires assessing their mental and physical health (EDE-Q, PHQ-9, MSI-BPD, GAD-7, and SF-12). The primary outcome is the evaluation of the severity of the eating disorder, measured with the EDE-Q. Secondary outcomes will be derived from the additional questionnaires and will include body mass index (BMI), menstrual status, follow-up data, general well-being, impact of the eating disorder, hospital readmission, suicide attempts, depressive symptoms, borderline personality traits, anxiety, quality of life, educational attainment, occupational status, and treatments received. We hypothesize that approximately 50% of patients will achieve remission three years after hospitalization.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

0 Years to 30 Years

Healthy volunteers

Inclusion criteria

* First full hospitalization in the eating disorders unit (EDU) at Robert Debré Hospital and diagnosis of AMP from 2016 to 2021 * No objection from the minor to the study * Proficiency and understanding of the French language * Access to digital technology (computer, smartphone, tablet, etc.)

Exclusion criteria

* Primary diagnosis of ARFID, other unspecified eating disorder

Design outcomes

Primary

Measure	Time frame	Description
Score of Eating Disorder Examination Questionnaire (EDE SQ) scale	6 months	the percentage of subjective cure

Secondary

Measure	Time frame	Description
Identification of predictive factors at admission for the trajectory (remission/relapse)	6 months	The number of hospitalizations related to anorexia nerovsa

Countries

France

Contacts

CONTACTColine STORDEUR, MD

coline.stordeur@aphp.fr33140032261

CONTACTAnael AYROLLES, MD

anael.ayrolles@aphp.fr33140032261

PRINCIPAL_INVESTIGATORColine STORDEUR, MD

Assistance Publique - Hôpitaux de Paris

Outcome results