Multiple Sclerosis
Conditions
Keywords
Neurorehabilitation, Telerehabilitation
Brief summary
The overall purpose of the present study is to investigate the effect of an advanced telerehablitation system (TRS) in persons with multiple sclerosis on mobility. The advanced telerhabilitation system is based on AI components, and delivers instant feedback to the partcipants. If the project is successful, it can help optimize exercise for those persons with multiple sclerosis who are either not able or willing to travel to a clinical setting for exericse.
Interventions
BEHAVIORALTelerehabilitation
Advanced telerehabilitation with a program made by specialized physiotherapists and delivered through the WizeCare system.
BEHAVIORALPaper-based exercise
Paper-based exercise instructions made by specialized physiotherapists.
Sponsors
MS Ireland
Tel Aviv University
University of Cagliari
University of Limerick
Danish Multiple Sclerosis Hospitals
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Definite diagnosis of MS according to the McDonald criteria (both relapse-remitting and progressive) * Expanded Disability Status Scale (EDSS) score of 2.5 to 6.5 or Patient Determined Disability Score (PDDS) of 2 to 6, indicating preservation of at least some ambulatory function, that is, the ability to walk 20 meters or more, independently, with or without the use of an assistive device * Willingness to travel to the local study site for the evaluation sessions, * Internet platform availability
Exclusion criteria
* comorbidities hindering participation in the study. * Individuals who have had a documented relapse and/or corticoid treatment during the past three months will be excluded, * Individuals with severe cognitive deficits who cannot follow simple instructions and/or consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 30 second sit to stand test | Baseline to 10 weeks | Measure of lower extremity muscle power and a proxy measure of mobility |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Reach Test | Baseline to 10 weeks | A measure of stability |
| Timed 25 feet foot walk test | Baseline to 10 weeks | A measure of walking speed |
| MiniBESTest | Baseline to 10 weeks | A measure of balance |
| Six minute walk test | Baseline to 10 weeks | A measure of walking endurance |
| Modified Fatigue Impact Scale | Baseline | Patient-reported measure of fatigue |
| 12 item Multiple Sclerosis Walking Scale | Baseline to 10 weeks | Patient-reported outcome of walking function |
| Multiple Sclerosis Impact Scale | Baseline to 10 weeks | Patient-reported measure on the impact of multiple sclerosis |
| Short Physical Performance Battery | Baseline to 10 weeks | Meaure of balance, walking function and lower extremity muscle strength |
| State-Trait Anxiety Inventory | Baseline to 10 weeks | Patient-reported measure of anxiety |
| Quick Inventory of Depression Symptomology | Baseline to 10 weeks | Patient-reported measure of depressive symptoms |
| Client Services Receipt Inventory | Baseline to 10 weeks | Patient-reported measure of used health services |
| Digital Health Literacy Scale | Baseline | Patient-reported measure of digital health literacy |
| Telehealth Usability Questionnaire | 10 weeks | Patient-reported measure of telehealth usability |
| Semi-structed interview | 10 weeks | A semi-structured interview on the satisfaction with the telerehabilitation system |
| EQ-5D-5L | Baseline to 10 weeks | Patient-reported measure of quality of life |
Countries
Denmark, Ireland, Israel, Italy
Outcome results
None listed