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Mediterranean Diet vs DASH and MIND in T2DM

The Effect of the Mediterranean Diet on Metabolic Parameters in Individuals With Type 2 Diabetes: A Comparative Evaluation With the DASH and MIND Diets

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07310225
Enrollment
90
Registered
2025-12-30
Start date
2024-01-01
Completion date
2024-09-30
Last updated
2025-12-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

Mediterranean diet, DASH diet, MIND diet

Brief summary

In our study, we aimed to comparatively evaluate the relative effects of the Mediterranean, DASH, and MIND diets on metabolic parameters in individuals with type 2 diabetes. The study was conducted on 90 individuals diagnosed with T2DM according to the American Diabetes Association diagnostic criteria (fasting blood glucose ≥ 126 mg/dL, 2-hour blood glucose ≥ 200 mg/dL during an oral glucose tolerance test (OGTT), or HbA1c ≥ 6.5% (48 mmol/mol)). Volunteers who participated in the study completed a questionnaire form that included sociodemographic characteristics. In addition, participants' anthropometric measurements (body weight (BW), height, waist circumference (WC), hip circumference (HC), body mass index (BMI)), biochemical parameters (fasting blood glucose, hbA1c (%), LDL-cholesterol, triglycerides, total cholesterol), Visceral Adiposity Index (VAİ), body composition analyses (Fat Mass (FM (%), Fat-Free Mass (FFM) (kg), Basal Metabolic Rate (BMR) (kcal), Visceral Fat Area (VFA) (%)), nutritional status (food consumption frequency, food consumption record, Mediterranean Diet Scale, DASH diet adherence score, and MIND diet adherence score) were evaluated.

Interventions

OTHERNo intervention (observational study)

No intervention (observational study)

Sponsors

Abant Izzet Baysal University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Individuals over 19 years of age * Individuals who are literate * Individuals diagnosed with Type 2 diabetes

Exclusion criteria

* Individuals who have had an acute infection or inflammatory disease within the past month * Individuals with chronic infectious or inflammatory diseases * Individuals with cancer

Design outcomes

Primary

MeasureTime frameDescription
Height9 monthsHeight was measured using a stadiometer with the participant's head positioned in the Frankfort plane and feet placed together.
Waist Circumference (WC)9 monthsWC was measured at the midpoint between the lowest rib and the iliac crest (cristal point) using a flexible measuring tape.
Questionnaire Form9 monthsSociodemographic characteristics of the individuals (age, gender, smoking and alcohol use) were questioned.
Body Weight (BW)9 monthsBW was measured using a calibrated digital scale placed on a flat, tiled surface. The scale was sensitive to 100 grams.
Hip Circumference (HC)9 monthsHC was measured at the widest point of the hips using a flexible measuring tape.
Body Mass Index (BMI)9 monthsBMI was calculated by dividing body weight (in kilograms) by the square of height (in meters): BMI = weight (kg) / height² (m²).
Fasting Blood Glucose9 monthsFasting blood glucose was measured using standard laboratory techniques during routine outpatient visits.
Triglycerides9 monthsTriglyceride levels were measured via fasting blood samples analyzed in the outpatient clinic laboratory.
LDL-Cholesterol9 monthsLDL-cholesterol was measured from fasting serum samples using standard enzymatic colorimetric methods.
Total Cholesterol9 monthsTotal cholesterol was measured using routine biochemical analysis in a certified laboratory.
HbA1c (%)9 monthsFasting blood glucose was measured using standard laboratory techniques during routine outpatient visits.
Abdominal obesity index (VAI)9 monthsAbdominal obesity index (VAI): VAI has been used to assess abdominal obesity. VAI (Men) = \[Waist circumference (cm) / (36.58 + (1.88 × BMI)\] × (triglycerides / 1.03) × (1.31 / HDL-C) , VAI (Women) = \[Waist circumference (cm) / (36.58 + (1.88 × BMI)\] × (triglycerides / 0.81) × (1.52 / HDL-C)
Body Fat Mass (FM) (%)9 monthsObtained using a bioelectrical impedance analysis (BIA) device (Tanita Innerscan BC 401, Japan).
Basal Metabolic Rate (BMR) (kcal)9 monthsBioelectrical impedance analysis (BIA) device (Tanita Innerscan BC 401, Japan) was used.
Fat-Free Mass (FFM) (kg)9 monthsbioelectrical impedance analysis (BIA) device (Tanita Innerscan BC 401, Japan).
Visceral Fat Area (VFA) (%)9 monthsBioelectrical impedance analysis (BIA) device (Tanita Innerscan BC 401, Japan).
Food consumption frequency9 monthsParticipants were asked about the foods they consumed in the past month from seven groups, including five basic food groups (meat and meat products, milk and dairy products, bread and grains, vegetables and fruits, sugars and fats), beverages, and fast food. Participants were asked how often and in what quantities they consumed these foods using eight options: every meal, every day, 5-6 days a week, 3-4 days a week, 1-2 days a week, once every 15 days, once a month, and never. In evaluating food consumption records, responses regarding food consumption frequency were calculated using food consumption frequency. The amounts of food and beverages consumed were multiplied by 3 for every meal, '1' for every day, 0.7855 for 5-6 times a week, 0.498 for 3-4 times a week, 0.2145 for 1-2 times a week, 0.067 for once every 15 days, and 0.033 for once a month to obtain the daily average amounts.
Food consumption record9 monthsA single-day food consumption record was obtained using the 24-hour recall method to determine participants' food consumption patterns. The Food and Nutrition Photo Catalog was used to estimate portions to ensure that the amounts of food consumed were assessed accurately and reliably. Based on these records, daily energy and nutrient intakes were calculated using the Nutrition Information System (BEBİS) software, based on the type and amount of food consumed by individuals in the last 24 hours.
DASH diet compliance9 monthsIndividuals' DASH diet compliance scores were calculated based on their food consumption frequency after their energy requirements were calculated. The highest possible score on the DASH diet compliance scale is 8.0. A score of 4.5 or above is considered 'high compliance', while a score below 4.5 is considered 'low compliance'.
Mediterranean diet adherence scale9 monthsThe Mediterranean Diet Scale was used to determine individuals' adherence to the Mediterranean diet. This scale consists of a total of 14 questions, 2 of which relate to food consumption habits and 12 of which relate to food consumption frequency. Each question is scored as either 0 or 1 point. The scale's scoring range is set at 0-14 points.
MIND diet compliance score9 monthsIt includes a total of 15 different food groups, consisting of ten groups that protect brain health and five groups that harm brain health. Individuals' food consumption records and frequency of food consumption were examined, and the consumption amounts of foods belonging to these 15 groups were divided into portions and evaluated according to the scoring system. This scale is scored from 0 to 15, and there is no cutoff point for determining compliance with the MIND diet.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026