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Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator

Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07308015
Enrollment
200
Registered
2025-12-29
Start date
2025-06-16
Completion date
2026-06-12
Last updated
2025-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinitis Sicca

Brief summary

To observe the therapeutic effect of sodium hyaluronate adjustable nasal irrigator on various types of rhinitis sicca and compare it with the therapeutic effect of the commonly used physiological seawater nasal spray in clinical practice.

Interventions

DRUGPhysiological seawater adjustable nasal irrigator

Nasal spray of Physiological seawater.

DRUGSodium hyaluronate adjustable nasal irrigator

Nasal spray of Sodium hyaluronate

Sponsors

China-Japan Union Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Symptoms: Dry nose sensation, little and thick nasal discharge, nosebleeds, itchy nasal cavity, and dryness in the nasopharynx. Physical signs: Nasal endoscopy often reveals dry and congested nasal mucosa, which appears grayish-white or dark red, losing its normal luster. There are often dry, thick secretions, scabs or blood scabs on it. The surface of the nasal mucosa is eroded and ulcers occur. The mucosal lesions are most obvious in the anterior part of the nasal cavity. A diagnosis can be made if one or more of the above symptoms and signs are present.

Exclusion criteria

1. Those with dry rhinitis and chronic inflammation of the lower respiratory tract. 2. Those confirmed by examination to be caused by certain latent lesions in the mouth, nose, throat, esophagu.s, neck or the whole body 3. Those who have used drugs for treating dry rhinitis or other medications within the past 30 days. 4. Pregnant or lactating women. 5. Those who are allergic to this medicine. 6. Those with severe cardiovascular, liver, kidney and hematopoietic system diseases, etc. 7. Mentally ill patients.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale (VAS)Two weeks after the treatment

Secondary

MeasureTime frame
Nasal endoscopy examination scoreTwo weeks after the treatment

Countries

China

Contacts

Primary ContactCuida Meng, Doctor
mengcd@jlu.edu.cn86+13596096000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026