Early-Onset Type 2 Diabetes
Conditions
Keywords
Integrated Traditional Chinese and Western Medicine, Precision Management, Personalized Management, Early-Onset Type 2 Diabetes
Brief summary
This project will leverage a large-scale cohort of early-onset type 2 diabetes patients to conduct innovative prospective clinical research. By integrating traditional Chinese medicine diagnostic information, clinical data, laboratory results, continuous glucose monitoring, genetic information, multi-omics data, and multi-modal monitoring data, and utilizing advanced data analysis methods such as deep learning, the project aims to establish a comprehensive monitoring, precise classification, and personalized diagnosis and treatment model-a holistic management approach integrating traditional Chinese and Western medicine for early-onset type 2 diabetes. This initiative is expected to enhance the management of early-onset type 2 diabetes, improve treatment outcomes and quality of life for affected patients, pioneer an innovative path for personalized integrated traditional Chinese and Western medicine management in this population, and promote the application of precision medicine in diabetes prevention and treatment.
Interventions
OTHERNo interventions
No interventions
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Inclusion criteria
* The age at diabetes diagnosis is ≥18 years but \<40 years.
Exclusion criteria
* The clinical diagnosis was type 1 diabetes, and at the time of enrollment, antibody levels or insulin/C-peptide results still supported the original diagnosis. There were clear secondary factors contributing to hyperglycemia, such as Cushing's syndrome or pheochromocytoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Score | Through study completion, an average of 3 months |
| HbA1c | Through study completion, an average of 3 months |
Secondary
| Measure | Time frame |
|---|---|
| Total Cholesterol | Through study completion, an average of 3 months |
| Triglycerides | Through study completion, an average of 3 months |
| Low-Density Lipoprotein Cholesterol | Through study completion, an average of 3 months |
| Fasting Blood Glucose | Through study completion, an average of 3 months |
| High-Density Lipoprotein Cholesterol | Through study completion, an average of 3 months |
Outcome results
None listed