Cancer Patients Referred to do PET/CT Study
Conditions
Keywords
SUV measurements , correction, PET/CT
Brief summary
-To measure SUVs by using different correction methods in oncological PET/CT imaging.
Detailed description
-To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area.
Interventions
* Patients will fast for at least 4 hrs before imaging with blood glucose level (\<200 mg/dl) before intravenous administration of F18-FDG. * Imaging will be performed approximately 45 to 60 min after 18F-FDG injection, an imaging field of view from the base of skull to mid-thighs with the arms above the head whenever possible is used or otherwise the arms are positioned beside the body.
Sponsors
Study design
Eligibility
Inclusion criteria
* Cancer patients (\> 18 years old) referred to nuclear medicine unit to do F18-FDG PET/CT study.
Exclusion criteria
* Patients \< 18 years old. * Patients with increased FDG uptake on tissue associated with non-malignant causes such as diffuse bone marrow FDG uptake or inflammatory. * Patients with extensive metastasis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| -To measure SUVs by using different correction methods in oncological PET/CT imaging. | 1/12/2025 to 1/10/2027 | -To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To determine if SUVbsa is more accurate than SUVbw in obese patients. | 1/12/2025 to 1/10/2027 | -To determine if ''normalization of FDG uptake for the body surface area'' (SUVbsa) is independent of the patient's body size and is more reliable than SUVbw. |