Atherogenic Plasma Index, H Pylori Infection
Conditions
Brief summary
Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are important for heart health. Changes in lipid levels, such as higher triglycerides and lower good cholesterol (HDL), can increase the risk of cardiovascular disease. This study will examine whether H. pylori infection is linked to changes in lipid profiles, especially the Atherogenic Index of Plasma (AIP). AIP is a calculation based on triglycerides and HDL cholesterol that helps predict the risk of heart disease.
Interventions
DIAGNOSTIC_TESTurea breath test
Participants will undergo a urea breath test to confirm H. pylori infection status. Fasting blood samples will be collected to measure triglycerides and HDL cholesterol, and the Atherogenic Index of Plasma (AIP) will be calculated.
Sponsors
Tanta University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients older than 18 years. * Able to sign the written consent. * Willing to participate in the research and undergo H. pylori testing.
Exclusion criteria
* Unwilling to participate in the study. * History of severe metabolic disorders. * Taking medications that affect adipose tissue metabolism. * History of gastric surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Atherogenic Index of Plasma (AIP) | Baseline (single fasting blood sample at enrollment). | AIP is calculated as log10(triglycerides/HDL cholesterol). |
Countries
Egypt
Outcome results
None listed