Autism Spectrum Disorder
Conditions
Keywords
language
Brief summary
The aim of this study is to assess the effectiveness of a rhythmic auditory training program in improving language skills in children with Autism Spectrum Disorder (ASD) who have a language acquisition disorder. The program focuses on training children to reproduce the syllable rhythms of speech, and the study will evaluate the children's language skills before and after participating in the program.
Interventions
BEHAVIORALEEG recording
EEG recording while listening to natural sounds
BEHAVIORALPicture recognition test
Children will have 4 images in front of them and a sound recording will be played to tell them which image to choose. They will have to click on the one that corresponds to what was said in the sound recording.
Sponsors
IHU reConnect
Institut Pasteur
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
3 Years to 6 Years
Healthy volunteers
No
Inclusion criteria
* aged between 3 and 6 at the time of inclusion * Have received a formal medical diagnosis of ASD * Have the consent of the parent(s) * Declaration of a language delay by the parents * Affiliated to social security or equivalent scheme
Exclusion criteria
* Conditions likely to interfere with the EEG and make its interpretation difficult, including severe epilepsy or cerebral malformations. * Treatments likely to interfere with the EEG (sedatives, psychostimulants, anxiolytics, antidepressants). * Known hearing impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in the progression of language acquisition measured by the difference in the number of images recognised in image recognition tests. | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| correlation between Phase Locking Value via EEG measurements of brain oscillatory activity during training and the language progression index. | 12 weeks |
| correlation between theta/gamma phase-amplitude coupling via EEG measurements of brain oscillatory activity during training and the language progression index. | 12 weeks |
| Comparison of Neural tracking of speech via EEG measurements of brain oscillatory activity before and after a session of listening to rhythmic sound. | 12 weeks |
| Comparison of theta/gamma frequency bands via EEG measurements of cerebral oscillatory activity before and after rhythmic auditory training | 12 weeks |
| correlation between Neural tracking via EEG measurements of brain oscillatory activity during training and the language progression index. | 12 weeks |
| Comparison of theta/gamma Phase-amplitude Coupling in auditory cortical areas via EEG measurements of cerebral oscillatory activity before and after rhythmic auditory training | 12 weeks |
| correlation between theta/gamma power via EEG measurements of brain oscillatory activity during training and the language progression index. | 12 weeks |
| correlation between Neural tracking via EEG measurements of brain oscillatory activity during training and the language progression index | 24 weeks |
| Comparison of Phase Locking Value via EEG measurements of cerebral oscillatory activity before and after rhythmic auditory training | 12 weeks |
Outcome results
None listed