Prevalence of Sarcopenia in Patients Admitted to ICU and Its Progression During Hospitalization.

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07303335

Acronym

SARC-ICU

Enrollment

100

Registered

2025-12-24

Start date

2025-05-14

Completion date

2026-02-28

Last updated

2025-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bio-Impedance Measurements, Body Composition Measurement, Critical Illness, Intensive Care (ICU) Myopathy, Sarcopenia, Ultrasound Evaluation

Brief summary

This is a prospective, observational study at the ICU of Hospital Mútua de Terrassa, running from May to December 2025. The primary goal is to determine the prevalence of sarcopenia in adult patients requiring more than 48 hours of mechanical ventilation. Sarcopenia is assessed using the SARC-F score, impedanciometry, and quadriceps ultrasound. Secondary aims include tracking the development of ICU-Acquired Weakness (ICU-AW) using the MRC score. All data is collected anonymously after obtaining informed consent.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Older than 18 years old. * Expected duration of mechanical ventilation (MV) exceeding 48 hours.

Exclusion criteria

* Refusal to participate. * Mechanical ventilation not exceeding 48 hours. * Do-not-resuscitate (DNR) orders or limitations of therapeutic effort upon admission.

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of sarcopenia at the time of ICU admission.	Baseline at admission to ICU	Describe the prevalence of sarcopenia at the time of ICU admission in patients with an expected duration of mechanical ventilation (MV) exceeding 48 hours.

Secondary

Measure	Time frame	Description
Detecting patients who develop ICU-Acquired Weakness (ICU-AW) and/or prolonged mechanical ventilation weaning	From ICU admission to 30 days follow-up	Detecting patients who develop ICU-Acquired Weakness (ICU-AW) and/or prolonged mechanical ventilation weaning, defined as failure of definitive disconnection from mechanical ventilation
Detecting the appearance of other complications	From admission to 30 days follow up	Detecting the appearance of other complications during admission such as: the appearance of refeeding syndrome or increased prevalence of insulin resistance.

Countries

Spain

Outcome results