Liver Fibrosis
Conditions
Keywords
Liver fibrosis, Type III glycogen storage disease, Liver fibrosis in pediatric patients
Brief summary
Patients with type III glycogen storage disease (GSDIII) can develop liver fibrosis, which can be complicated by liver failure or even hepatocellular carcinoma. Since the beginning of the 21st century, non-invasive techniques for assessing fibrosis, such as liver elastography, have been developed. These techniques often make it possible to avoid liver biopsies during patient follow-up and have already been validated in the management of several diseases in adults. These techniques are also beginning to be recommended for monitoring certain chronic liver diseases in children.
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 21 Years
Inclusion criteria
* Minors: from birth to 17 years * Adults: 18 to 21 years * Subjects being monitored for type III glycogen storage disease and having had at least one liver elastography measurement during their follow-up.
Exclusion criteria
\- Patients monitored for type III glycogen storage disease but who had never undergone liver elastography during their follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Liver elastography values | 1 hour after consultation | Liver fibrosis is classified into four stages, from 0 to 4: * F0 corresponds to the absence of fibrosis * F4 corresponds to established cirrhosis. |
Countries
France
Contacts
Primary ContactCamille WICKER, MD
Outcome results
None listed