Acute Ischemic Stroke
Conditions
Brief summary
Telemedicine-supported stroke care can provide standardized guidance to hospitals and regions with limited medical resources, thereby improving treatment outcomes for stroke patients in these areas. While this approach has been widely adopted in many developed countries, its efficacy in guiding basic-level hospitals to manage acute ischemic stroke requires further investigation through large-scale, high-quality studies. This study focused on patients with acute ischemic stroke who sought treatment at basic-level hospitals, aiming to investigate the efficacy and safety of treating acute ischemic stroke with telemedicine-supported management. Hospitals assigned to the experimental group received remote consultation guidance, quality control and professional training from expert teams at leading stroke centers, China National Center for Neurological Disorders. Hospitals in the control group did not receive telemedicine-supported management.
Interventions
OTHERTelemedicine-Supported Management
Receive round-the-clock 7×24h remote consultation guidance from expert teams at leading stroke centers, covering patient triage and initial assessment, thrombolysis decision-making, and treatment guidance. Undergo quality control for standardized workflow implementation, and professional training.
Sponsors
Capital Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hospital Inclusion Criteria: 1. Basic-level hospitals in China (Definition: Hospitals classified as secondary-level (Grade II) or below under China's Hospital Grading Management Standards, or hospitals located in counties/county-level cities). 2. Equipped with an emergency department and neurology ward capable of admitting stroke patients. 3. Equipped with CT and/or MRI capable of diagnosing AIS. 4. Equipped with intravenous thrombolytic drugs for acute ischemic stroke. * Patient Inclusion Criteria: 1. Age ≥ 18 years. 2. Diagnosed with acute ischemic stroke. 3. CT/MRI confirms absence of intracerebral hemorrhage. 4. Onset of stroke symptoms ≤ 4.5 hours. 5. pre-stroke mRS score ≤1. 6. Informed consent obtained from patient or their legal representative.
Exclusion criteria
* Hospital
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with mRS scores of 0-1 | 90 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of endovascular therapy receipt among eligible patients | 24 hours | — |
| Door-to-(thrombolysis)needle-time | 4.5 hours | The time calculation begins when the patient arrives at the hospital and ends upon receiving thrombolytic therapy. The theoretical range is 0 to 270 minutes. |
| Intravenous thrombolysis rate | 4.5 hours | — |
| mRS score | 90 days | Ranges from 0 to 6 points, with lower scores indicating better functional outcome. |
Countries
China
Contacts
CONTACTXunming Ji
CONTACTChuanjie Wu
Outcome results
None listed