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Deep Learning-Assisted Ultrasonic Diagnosis and Localization of Testicular Appendix Torsion

Deep Learning-Assisted Ultrasonic Diagnosis and Localization of Testicular Appendix Torsion: A Multicenter Retrospective Validation Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07301086
Enrollment
2000
Registered
2025-12-24
Start date
2026-01-31
Completion date
2026-05-31
Last updated
2025-12-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epididymitis, Testicular Appendix Torsion, Testicular Torsion

Keywords

Testicular Appendix Torsion, Deep Learning, Ultrasonic Diagnosis

Brief summary

Ultrasound data were both retrospectively and prospectively collected from the primary center and six other sub-centers. Combined with clinical diagnostic outcomes, the data labeling was completed by physicians with extensive clinical experience. In this study, ConvNeXtV2 was used as the classification network and YOLOv12 was adopted as the detection network.The retrospective dataset from the primary center was split into training, validation, and test subsets, on which the model was trained, validated, and tested respectively; additional validation was conducted on both retrospective and prospective datasets from the primary center and sub-centers.Meanwhile, four physicians were assigned to interpret the ultrasound data from the retrospective and prospective datasets from the primary center and sub-centers using two diagnostic methods-independent diagnosis and artificial intelligence (AI)-assisted diagnosis-and the diagnostic accuracy of these two approaches was further compared.By collecting and learning the treatment methods of patients in the primary center training set, predicting the treatment methods of patients in the sub-center datasets, and comparing the proportion of surgeries predicted by AI with the actual proportion of surgeries, the efficacy of the model was verified.

Detailed description

Ultrasound data were both retrospectively and prospectively collected from the primary center and six other sub-centers. Combined with clinical diagnostic outcomes, the data labeling was completed by physicians with extensive clinical experience. In this study, ConvNeXtV2 was used as the classification network and YOLOv12 was adopted as the detection network.The retrospective dataset from the primary center was split into training, validation, and test subsets, on which the model was trained, validated, and tested respectively; additional validation was conducted on both retrospective and prospective datasets from the primary center and sub-centers.Meanwhile, four physicians were assigned to interpret the ultrasound data from the retrospective and prospective datasets from the primary center and sub-centers using two diagnostic methods-independent diagnosis and artificial intelligence (AI)-assisted diagnosis-and the diagnostic accuracy of these two approaches was further compared.By collecting and learning the treatment methods of patients in the primary center training set, predicting the treatment methods of patients in the sub-center datasets, and comparing the proportion of surgeries predicted by AI with the actual proportion of surgeries, the efficacy of the model was verified.

Interventions

None listed

Sponsors

Ying Jiang
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
MALE
Age
1 Minutes to 18 Years
Healthy volunteers
Yes

Inclusion criteria

1. Age ≤ 18 years old 2. Underwent ultrasound examination due to acute scrotal pain (≤ 24 hours) 3. Patients clinically diagnosed with testicular appendage torsion (TAT)

Exclusion criteria

1. Poor ultrasound image quality (failure to identify testicular structures) 2. Incomplete clinical data (failure to confirm the diagnosis of testicular appendage torsion \[TAT\])

Design outcomes

Primary

MeasureTime frameDescription
Accuracy of deep-learning model verify four conditions:testicular appendage torsion;testicular torsion;epididymitis and normal conditionFrom image input to result generation is expected to be 24 hoursaccuracy of deep-learning model verify four conditions:testicular appendage torsion;testicular torsion;epididymitis and normal condition

Secondary

MeasureTime frame
Number of Participants with Acute Scrotal PainFrom enrollment begin to the end is expected to be 5 months
The accuracy rate of clinicians in diagnosing and localizing testicular appendix torsionFrom the begin of Clinicians diagnose and locate to the end is expected to be 15 days
The accuracy rate of the Deep learning model in predicting the treatment modality for testicular appendix torsion,conservative treatment or surgeryFrom the begin of the prediction of treatment for testicular appendix torsion by Deep learning model to the end is expected to be 24 hours

Countries

China

Contacts

Primary ContactYing Jiang, Master Degree
Jiang_ying@zju.edu.cn86-19883203100
Backup ContactJuntao Jiang, Master Degree
juntaojiang@zju.edu.cn86-13968107281

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026