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Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries

Efficacy of Intranasal Sphenopalatine Ganglion Block by Lidocaine Spray for Partial Turbinectomy Surgeries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07299630
Acronym
SPG block
Enrollment
50
Registered
2025-12-23
Start date
2025-12-20
Completion date
2026-02-01
Last updated
2025-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Turbinate Surgery, Sphenopalatine Block

Keywords

SPG block, lidocaine spray, partial turbinectomy surgery

Brief summary

Nasal turbinectomy surgeries are usually done as day case surgeries as most patients are young with unremarkable comorbidities. However, considerations are still present towards patients of old age or those suffering from obesity or obstructive sleep apnea (OSA). Different techniques are still evolving to improve handling those patients to decrease complications, enhance recovery after surgery and increase patient satisfaction. Targeting sphenopalatine ganglion block by topical local anesthesia is a proposed technique that could help by decreasing peri-operative opioid consumption.

Detailed description

Patients undergoing turbinectomy usually suffer from chronic nasal congestion with wide spectrum of symptoms ranging from headache and breathing difficulty to sleep disorders and obstructive sleep apnea that could affect daily life . Usually the surgery is done as a day case surgery in patients without major comorbidities. Points of concern to achieve smooth outcome and enhance recovery include pain management, better surgical field for both patient and surgeon satisfaction. One approach for these goals include regional nerve blocks for the innervation of the nose . Spheno Palatine Ganglion (SPG) block was tested with a good results for blocking autonomic innervation and subsequent decrease in pain and opioid consumption. Blockage of SPG has many approaches either trans nasal or trans oral but both are invasive and needs trained hands to do Locally infiltrating lidocaine over nasal mucosa either by lidocaine spray or a lidocaine soaked gauze was also tested in nasal surgeries with good results but doubts about duration of action of lidocaine spray is a concern that may affect post-operative pain management Targeting SPG noninvasively by lidocaine spray is proposed technique that may offer easier approach for this type of surgeries. Although concerns about effectiveness of the spray to reach and block SPG was raised before , many studies examined this approach to control headache or trigeminal neuralgia with great success.

Interventions

Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW). and morphine after intubation

o Analgesia will be offered by fentanyl in induction according to Actual Body Weight (ABW) and then Lignocaine spray 10% 10 puffs will be applied on to the nasal cavity after directing the spray applicator parallel to the nasal floor until resistance is felt after intubation and application of nasal decongestant, in the two nostrils

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Undergoing elective partial turbinectomy surgery

Exclusion criteria

* Patient refusal * Kidney or liver impairment * Pregnant or breast-feeding women * Allergy to any of the drugs used in the study * OR time more than 90 min

Design outcomes

Primary

MeasureTime frameDescription
fentanyl dosesintraoperativeTotal doses of fentanyl rescue doses intraoperative

Secondary

MeasureTime frameDescription
Visual analog Scoreup to 12 hours post operativeVAS score post operative

Countries

Egypt

Contacts

Primary ContactAbdallah soudi, M.D.
dr.soudi2014@med.asu.edu.eg02- 01111228925

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026