Low-Density-Lipoprotein-cholesterol Level, Risk Factors, Stroke
Conditions
Keywords
Stroke, Risk factors
Brief summary
Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.
Detailed description
Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature. These clinically relevant issues have not been studied extensively in the Middle East where most of the studies in atherosclerotic cardiovascular disease have focused on acute coronary syndrome more than stroke. Exploring new information on risk factors of stroke in this region that helps fill some of the knowledge gaps. Stroke has been attributed, in the majority of cases, to the traditional four standard modifiable risk factors of hypertension, type 2 diabetes, dyslipidemia, and cigarette smoking. However, ethnicity and geography account for the interregional differences of the prevalence of risk factors in patients with stroke. The Jo-SMMART ill evaluate risk factors in 2000 stroke patients in Jordan as a representative of the Middle Eastern population, the prevalence of those with none of the 4 risk factors and the differences in clinical profiles and demographic features on those with risk factors and those with no risk factors. Lipid profile and use of lipid lowering agents will also be evaluated, and furthermore the die0fferneces between young vs old, and men vs women stroke patients ill be addressed.
Interventions
None listed
Sponsors
Jordan Collaborating Cardiology Group
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Diagnosis of stroke upon admission to the hospital * Adult aged 18 years or older * Available lipid profile on hospital admission
Exclusion criteria
* Stroke diagnosis unconfirmed * age younger than 18 years * No available lipid profile on admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of hypertension in stroke patients (survey interview) | Baseline | BP more 140/90 or known diagnosis of high blood pressure or patient already on blood pressure medication |
| Prevalence of type 2 diabetes in stroke patients (survey interview) | BASELINE | HbA1c more than 6.5%, or known diagnosis of type 2 diabetes or patient already on anti diabetes medications |
| Prevalence of elevated serum level of low density lipoprotein cholesterol in stroke patients (survey interview) | BASELINE | Elevated serum level of low density lipoprotein cholesterol \> 55 mg/dl or patient already on lipid lowering medication |
| Prevalence of current cigarette smoking in stroke patients (survey interview) | BASELINE | Known current cigarette smoking of any number of cigarettes per day |
| Use of lipid lowering therapy (survey interview) | BASELINE | Current use of statin, ezitimibe, PCS9 inhibitor of small interfering RNA agent to lower the LDL-C |
Countries
Jordan
Contacts
Primary ContactLaith Habahbeh, MD
Backup ContactAyman Hammoudeh, MD, FACC
Outcome results
None listed