3D Liver Volumetry

Accuracy of Individualized 3D Reconstruction in Predicting Liver Resection Volume: A Prospective Study

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07297615

Enrollment

Registered

2025-12-22

Start date

2026-04-01

Completion date

2028-09-30

Last updated

2026-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

3D-reconstruction, Liver, Liver Cancer, Liver Surgery, Surgical Planning, Volumetric Analysis

Brief summary

The study aims to improve preoperative evaluation of liver resection volume in patients undergoing major hepatectomies. Accurate prediction of the planned resection and the future liver remnant (FLR) is critical to minimize the risk of postoperative liver failure, which is associated with increased morbidity and mortality. Conventional imaging-based volumetry may have limited accuracy. This study investigates the use of individualized 3D liver models combined to enhance visualization and volumetric analysis of liver anatomy and resection boundaries. Patients are recruited in the liver outpatient clinic and, upon consent, preoperative 3D models are created using Medics 3D. During surgery, the planned resection is guided by the individualized 3D models. Postoperatively, the resected specimen undergoes CT-based volumetry to compare the predicted resection volume from the 3D model with the actual volume. Routine postoperative follow-up is conducted. The study aims to optimize surgical planning, enhance the accuracy of future liver remnant prediction.

Interventions

DIAGNOSTIC_TEST3d reconstruction

Preoperatively, every patient in this study will undergo an individualized 3D reconstruction of their liver to perform accurate volumetry.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients (≥18 years) undergoing open or minimally invasive major liver resection at the Clinical Division of General, Visceral and Transplant Surgery who provide written informed consent prior to participation will be included.

Exclusion criteria

* Patients unable to provide informed consent will be excluded. * Minor resections. * Contraindications to MRI.

Design outcomes

Primary

Measure	Time frame
Assessment of the preoperative volumetry of the liver portion planned for resection using a 3D model and comparison with the postoperative resection specimen volume.	Approximately 2-3 weeks are required between preoperative volumetry and postoperative volumetry comparison.

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026