Prostate
Conditions
Brief summary
Objectives:There are numerous auxiliary methods to improve the accuracy of pathology results regarding prostate biopsy. However, there is no consensus on how to achieve precise targeted biopsy. This paper explores whether using data obtained through the three-dimensional reconstructed image to locate biopsy points can assist in prostate targeted biopsy. Methods: This study is prospective. Between January 1, 2022, and June 30, 2025, our center conducted prostate biopsies on a total of 436 patients who met the criteria for prostate biopsy and exhibited suspicious lesions (PI-RADS 3-5), totaling 471 lesions. Prior to the biopsies, 3D Slicer software was utilized to perform three-dimensional reconstructions of the pelvic organs. Three-dimensional imaging was employed to measure the biopsy path data, guiding targeted biopsies. This study combined software-assisted targeted biopsies with systematic biopsies and conducted an analysis to assess the feasibility of this approach.
Interventions
PROCEDUREProstate biopsy
All participants underwent both targeted and systematic biopsies, along with three-dimensional reconstructed image-assisted prostate targeted biopsy,and software-assisted fusion targeted biopsy
Sponsors
Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
Patients meet the criteria for prostate biopsy and exhibited suspicious lesions (PI-RADS 3-5)
Exclusion criteria
Patients with advanced prostate cancer and those with severe coagulopathy or other conditions unsuitable for prostate biopsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| detection rates of clinically significant prostate cancer | 2022.01~2025.06 |
Countries
China
Outcome results
None listed