Otomycosis
Conditions
Brief summary
This study compares two topical agents for the treatment of fungal infection of the external auditory canal: boric acid and a 10% povidone-iodine solution
Interventions
DRUGBoric acid
Boric acid is topically applied to the external auditory canal for treatment of otomycosis
DRUGPovidone iodine 10%
10% povidone iodine solution is topically applied to the external auditory canal for the treatment of otomycosis
Sponsors
Mansoura University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* all consecutive patients with otomycosis, recruited from the outpatient clinic during the study duration
Exclusion criteria
* tympanic membrane perforation * previous ear surgery * significant medical co-morbidities such as poorly controlled diabetes or immunocompromised patients * patient refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| objective clinical response | Days 7, 14, and 28 after treatment | clinical response is assessed by ear examination by presence or absence of fungal hyphae inside the external auditory canal |
| Microbiological response | day 28 after treatment | Microbiological response is evaluated by obtaining cultures from the external auditory canal searching for fungal growth |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| subjective pain response | days 7, 14, and 28 after treatment | pain is evaluated on a visual analogue scale from 0 to 10 |
| subjective itching response | days 7, 14, and 28 after treatment | itching is evaluated on a visual analogue scale from 0 to 10 |
Countries
Egypt
Outcome results
None listed