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Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block

Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block: A Prospective Observational Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07295184
Enrollment
90
Registered
2025-12-19
Start date
2026-05-12
Completion date
2026-12-25
Last updated
2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rebound Pain Impact After Hip Surgery With Nerve Block

Brief summary

Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly. Postoperative delirium is associated with serious consequences, including prolonged intensive care unit stay, increased complication rates, higher mortality risk, and rising healthcare costs. The incidence of Postoperative delirium after hip fracture surgery has been reported to range between 13% and 55.9%, indicating a substantial clinical burden. Effective postoperative pain control is critical not only for maintaining quality of life but also for preserving cognitive well-being. In this context, peripheral nerve blocks are frequently used for pain management following hip surgery.

Detailed description

Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly. Postoperative delirium is associated with serious consequences, including prolonged intensive care unit stay, increased complication rates, higher mortality risk, and rising healthcare costs. The incidence of Postoperative delirium after hip fracture surgery has been reported to range between 13% and 55.9%, indicating a substantial clinical burden. Effective postoperative pain control is critical not only for maintaining quality of life but also for preserving cognitive well-being. In this context, peripheral nerve blocks are frequently used for pain management following hip surgery. In recent years, the Pericapsular Nerve Group block and the supra-inguinal fascia iliaca block have gained attention as regional anesthesia techniques that provide effective analgesia by targeting the nerve branches innervating the anterior capsule of the hip joint.

Interventions

OTHERPeripheral nerve block applied

Pericapsular Nerve Group block and the supra-inguinal fascia iliaca block applied

OTHEROnly multimodal analgesia applied

Postoperative analgesia (paracetamol 1000 mg intravenously every 8 hours and celecoxib 200 mg orally every 12 hours)

Sponsors

Konya City Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients aged 18-80 * ASA I-III risk groups * Undergoing elective hip surgery

Exclusion criteria

* Preoperative history of delirium, dementia, or major neurological disease * Present cognitive impairment or severe hearing or visual impairment that could affect pain assessment * Development of mechanical ventilation requirement in the intensive care unit; Need for bilateral hip surgery * Failure to provide meaningful analgesia after block application due to surgical pain outside the scope of the block * Patient's inability to complete the pain diary during postoperative follow-up; * Urgent hip surgery * Voluntary failure to give consent or request to withdraw from the study.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of delirium72 hoursThe incidence of delirium will be evaluated in the first 72 hours postoperatively in the intensive care unit.

Countries

Turkey (Türkiye)

Contacts

CONTACTHasan SENAY, M.D.
hasansenay@msn.com05055078822

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026