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Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke

Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07294274
Enrollment
488
Registered
2025-12-19
Start date
2025-11-01
Completion date
2026-07-20
Last updated
2026-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Depression

Brief summary

Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive impairments, greater economic burdens, and lower quality of life, but also brings additional medical expenses and care pressure to families. Society also needs to bear higher medical costs. Currently, the early diagnosis of PSD is difficult, which may lead to poor prognosis after stroke. This study aims to utilize machine learning technology to integrate multi-dimensional indicators of patients with ischemic stroke, establish a risk prediction model for PSD, and assist in early, accurate, and individualized assessment of PSD risk in clinical practice.

Interventions

DIAGNOSTIC_TESTGroup patients based on whether they have been diagnosed with PSD.

Group patients based on whether they have been diagnosed with PSD.

Sponsors

Min Su
Lead SponsorOTHER
Chongqing Traditional Chinese Medicine Hospital
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with acute ischemic stroke; * Admission within 7 days of symptom onset; * The patient and/or the family members sign a written informed consent form.

Exclusion criteria

* Confusion of consciousness,severe cognitive impairment, etc * Individuals with a history of depression, schizophrenia, bipolar disorder, etc; * Individuals unable to participate in neuropsychological examinations due to hearing im pairments, lack of coordination, or neurological deficits, including se vere aphasia.

Design outcomes

Primary

MeasureTime frame
The number of post-stroke depression (PSD) that occurs 3 months after stroke3 months after stroke

Countries

China

Contacts

CONTACTYanping Zhang
zhangyp8415@163.com86+15223049366

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026