Osteoarthritis (OA), Spinal Cord Injuries (SCI)
Conditions
Keywords
spinal cord injury, osteoarthritis, musculoskeletal ultrasound, talar cartilage
Brief summary
Spinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury patients with healthy subjects. The secondary aim is to investigate a correlation between the talar cartilage thickness and disease-related parameters. The patient group is to be assessed for talar cartilage thickness (via ultrasound), functional status, spasticity, and ambulation levels.
Interventions
None listed
Sponsors
Gaziosmanpasa Research and Education Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Aged between 18 to 60 years, * Cervical, thoracal or lumber level of spinal cord injury * AIS (American Spinal Injury Association Impairment Scale) Level A, B, C, or D * Assisted ambulation of any kind * Literacy * Giving oral and written consent to participate in the study
Exclusion criteria
* Patients with sacral level injury * AIS E * MAS 4 level of spasticity * History of any lower extremity operation * History of fracture * Botulinum toxin injection in the last 6 months * Existing diagnosis of any rheumatologic or endocrine diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Talar cartilage thickness | Baseline | The talar cartilage of both lower extremities are to be assessed with ultrasound |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Independence Measure (FIM) score | Baseline | Functional Independence Measure scores will be held for the patient group in order to assess functional independence. This 18-item scale ranges between 18-126, higher scores indicating better outcomes. |
| Modified Ashworth Scale (MAS) | Baseline | The spasticity level of patients are to be recorded for both ankle flexor and extensors via Modified Ashworth Scale. This scale ranges from 0 to 4; 0 indicating no spasticity, and 4 indicating severe increase in muscle tone with rigid joint. |
| Walking Index for Spinal Cord Injury II (WISCI II) | Baseline | Ambulatory status of the patients will be recorded with this measuring scale, ranging between 0 (non ambulatory) to 20 (able to walk 10 meters with no devices/orthosis/assistance). |
Countries
Turkey (Türkiye)
Outcome results
None listed