Chronic Kidney Disease, Muscle Weakness, Physical Fitness, Physical Therapy Modalities, Renal Insufficiency, Chronic, Sarcopenia
Conditions
Keywords
chronic kidney disease, renal patients, muscle strength assessment, isokinetic testing, surface electromyography, physiotherapy, occupational therapy, functional evaluation, therapeutic exercise
Brief summary
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.
Detailed description
Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity. This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will: 1. Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry). 2. Implement and evaluate an online therapeutic exercise program supervised by physiotherapists. The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.
Interventions
DEVICEReliability Assessment
Device: Isokinetic dynamometer and mDurance® surface EMG Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb
BEHAVIORALOnline Therapeutic Exercise
Behavioral: Online therapeutic exercise program 8-10 week supervised online program including resistance and mobility exercises
Sponsors
University of Extremadura
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* ≥18 years old. * Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant). * Member of ALCER Association (Badajoz or Cáceres). * Medical clearance for physical testing/exercise.
Exclusion criteria
* Severe cognitive or communication impairment. * Unstable cardiovascular or musculoskeletal conditions. * Refusal to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Test-retest reliability of surface EMG (Electromiography) activation. | 7-10 days | RMS (root mean square). microvolts |
| Test-retest reliability of isokinetic strength | 7-10 days | Intraclass Correlation Coefficient - ICC. Strength (kilograms) |
| Change in handgrip and limb strength measured by VALD dynamometry | Baseline and 12 weeks | strength (kilograms) |
Countries
Spain
Outcome results
None listed