Activities of Daily Living, Adverse Childhood Experience, Depressive Symptoms, Emotional Regulation, Mental Health, Mental Well-being, Myasthenia Gravis, Psychological Stress, Psychological Well-being, Quality of Life (QOL), Well-Being, Psychological
Conditions
Keywords
myasthenia gravis, adverse childhood experience, online learning program, positive mental health BMI learning program, emotional regulation, emotional stability, psychological well-being, mental health BMI
Brief summary
This study evaluated psychological health in patients with myasthenia gravis (MG) using an online behavioral program called the Positive Mental Health BMI Learning Program. The program consisted of four short video units focused on interpersonal support, emotional regulation, and personal meaning. Patients receiving care in the neurology outpatient clinic were invited to complete questionnaires before and after viewing the online program. Psychological well-being, depressive symptoms, daily functioning, and quality of life were assessed to describe participants' mental health status and changes observed over the course of the program.
Detailed description
Participants completed sociodemographic questionnaires, adverse childhood experiences (ACEs) assessments, and four psychological and disease-related measures: the Myasthenia Gravis Activities of Daily Living Scale (MG-ADL), the Myasthenia Gravis Quality of Life 15-item scale (MG-QOL15), the mental health BMI indicator (mBMI), and the Patient Health Questionnaire-9 (PHQ-9). The study collected baseline data prior to the online program and post-intervention data after completion of the four video units. Analyses examined associations between ACE exposure and psychological measures, as well as changes in clinical and psychological indicators across the intervention period.
Interventions
BEHAVIORALPositive Mental Health BMI Learning Program
The intervention consisted of the Positive Mental Health BMI Learning Program, a four-unit online behavioral program delivered through a closed Facebook group. Each video unit was approximately 15 minutes and focused on components of positive mental health, including interpersonal support, emotional regulation, and sense of meaning and self-worth. One unit was released each month over a four-month period. Participants completed pre-test assessments before the program and post-test assessments after completing all four units.
Sponsors
Jiann-Horng Yeh
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Masking description
This was an open-label study in which no masking was used. All participants and investigators were aware of the behavioral intervention being provided.
Intervention model description
All participants were enrolled into a single study group and received the same online behavioral intervention, the online Positive Mental Health BMI Learning Program. Pre-test and post-test assessments were completed by participants to measure psychological outcomes.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with a confirmed diagnosis of myasthenia gravis (MG) based on acetylcholine receptor antibody testing, single-fiber electromyography, repetitive nerve stimulation, or chest computed tomography. * Individuals able to clearly express their own intentions. * Individuals without cognitive impairment or psychiatric disorders. * Individuals who are able to use Facebook and who agree to participate in the study and provide written informed consent.
Exclusion criteria
* Individuals who do not have a diagnosis of MG. * Patients who are unable to communicate adequately in Mandarin, Taiwanese, English, or written form. * Individuals with head trauma, psychiatric symptoms, or cognitive impairment that may interfere with verbal expression.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the indicator of mental health BMI on well-being (mBMI) Score from baseline to post-intervention | Baseline to 4 months | The indicator of mental health BMI (mBMI) is a measure of positive psychological well-being that includes three domains: 1. Befriend (B), representing interpersonal support and closeness 2. Mindfulness (M), representing emotional stability and awareness 3. Identity (I), representing self-worth and meaning. Scores were collected before the intervention and after completion of the four-unit online program to evaluate changes in psychological well-being. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Patient Health Questionnaire-9 (PHQ-9) Score from baseline to post-intervention | Baseline to 4 months | The Patient Health Questionnaire-9 (PHQ-9) is a 9-item measure used to assess the severity of depressive symptoms. Participants completed the PHQ-9 before the intervention and again after completing the four-unit online program to evaluate changes in depressive symptom severity over time. |
| Change in Myasthenia Gravis Quality of Life 15-item (MG-QOL15) Score from baseline to post-intervention | Baseline to 4 months | The Myasthenia Gravis Quality of Life 15-item scale (MG-QOL15) is a disease-specific measure used to assess the impact of myasthenia gravis on daily functioning and overall quality of life. Participants completed the MG-QOL15 before the intervention and again after completing the four-unit online program to evaluate changes in disease-related quality of life. |
| Change in Myasthenia Gravis Activities of Daily Living (MG-ADL) Score from baseline to post-intervention | Baseline to 4 months | The Myasthenia Gravis Activities of Daily Living scale (MG-ADL) is an 8-item measure used to assess symptom severity and the impact of myasthenia gravis on daily functioning. Participants completed the MG-ADL before the intervention and again after completing the four-unit online program to evaluate changes in disease-related functional status. |
Countries
Taiwan
Outcome results
None listed