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Management of Supraventricular Tachycardias in Children

Management of Supraventricular Tachycardias in Children: A National Multicenter Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07291544
Enrollment
1400
Registered
2025-12-18
Start date
2000-01-01
Completion date
2025-09-30
Last updated
2026-01-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children, Management, Supraventricular Arrhythmias

Keywords

supraventricular arrhythmias, supraventricular tachycardia, children

Brief summary

Background Supraventricular tachycardias (SVTs) are the most common arrhythmic events in children, with an estimated incidence of 13 per 100,000 per year before the age of 18. Few large patient cohorts have been reported, as most published studies are single-center. Large-scale studies come from medico-administrative databases, which lack the granularity needed for detailed analysis of outcomes according to the therapies used and the type of SVT. Furthermore, although a large proportion of neonatal SVTs do not recur (spontaneous resolution of the accessory pathway), there are limited comparative data on the effectiveness of antiarrhythmic therapies specifically in children after the age of 1 year. Management therefore varies greatly, in part because current guidelines propose different therapeutic options based on low-level evidence. Objectives: * Describe the management of SVTs (antiarrhythmic therapies and catheter ablation) in children in France * Compare the effectiveness of different antiarrhythmic treatments according to age (\<1 year and \>1 year) and type of SVT * Analyze the incidence of adverse events and complications associated with antiarrhythmic treatments and catheter ablation

Interventions

OTHERManagement of children with supraventricular tachycardias

Observational analysis of the management of supraventricular tachycardias (antiarrhythmic drugs and catheter ablations)

Sponsors

Paris Cardiovascular Research Center (Inserm U970)
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Age \<18 years at the time of the first documented supraventricular tachycardia episode

Exclusion criteria

* Early postoperative supraventricular tachycardia (\<30 days) * Age ≥18 years at the first documented supraventricular tachycardia episode * Fetal tachycardias without postnatal recurrence * Atrial extrasystoles without sustained runs (\<30 seconds)

Design outcomes

Primary

MeasureTime frameDescription
Antiarrhythmic therapiesAt the time of the first supraventricular tachycardia recordedProportion of antiarrhythmic therapies used by age group (\<1 year and \>1 year)
Catheter ablationAt the time of first episode of supraventricular tachycardia or after recurrenceProportion of children referred for catheter ablation and age at ablation
Recurrence of supraventricular tachycardiaAt 1 year after antiarrhythmic drug initiationTime between antiarrhythmic therapy initiation and first recurrence, according to treatment and age

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026