Contrast-induced Nephropathy
Conditions
Brief summary
The aim is to assess the benefit of low dose oral amlodipine in renal protection from contrast induced nephropathy in diabetic patients in intensive care unit
Interventions
amlodipine group will receive low dose oral amlodipine ( 5 mg ) before iv contrast and every 12 hour for 48 hour
OTHERHydration
before the procedure patients will recieve iv bolus of 250 ml saline followed by continous infusion of 100 ml/h of normal saline
Sponsors
Minia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* adult patients of both sexes (18:70) diabetic patients with serum creatinine below 1.2 hemodynamically stable patients ASA physical status 2,3
Exclusion criteria
* patient refusal patients of chronic kidney diseases NPO patients serum creatinine above 1.2 Hypertensive patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measuring serum creatinine level | baseline | measuring serum creatinine level before the procedure and every day for 48 hours after |
Contacts
Primary ContactAndrew Shehata, Master
Outcome results
None listed