Soft Contact Lenses
Conditions
Keywords
soft contact lens, conjunctival hyperemia, image J analysis, efron degree system
Brief summary
Soft Contact Lens (SCL) use all over the world is still increasing. Ocular surface inflammatory reaction is the most common risk of using SCL. Currently, the standard used to assess this complication is the Efron Degree System (EDS), but it has high variability due its subjectivity. ImageJ gives more objective result with conjunctival vasodilation and vascular density assessment, so that complication management can be given earlier. Purpose: Evaluate the suitability of SDE with ImageJ analysis in assessing conjunctival hyperemia in SCL use within 2 weeks.
Detailed description
This is a paired prospective analytic study. Subjects with myopia who have not used SCL routinely before were instructed to use SCL for 14 days. Conjunctival inflammation were assessed with slit lamp examination before, at day 7, and day 14 of using SCL. Slit lamp pictures were analysed with EDS and ImageJ to be compared.
Interventions
DEVICEhydrogel soft contact lens
This study aim to analyze the conformity of hyperemia when evaluated by ophthalmologist using the Efron degree system compared to evaluation by a computerized model (Image J analysis )
Sponsors
Indonesia University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Masking description
Conjunctival inflammation degree evaluation was done with taking picture of conjunctiva using slit lamp by lead researcher. Picture was taken on day 0 (before using SCL), day 7, and day 14 of wearing SCL. Pictures then were analyzed with Efron Degree System (EDS) by 2 evaluators (both were ophthalmologist consultants) and with ImageJ application by lead researcher. ImageJ analysis was done to decide conjunctival vascular diameter and density. EDS evaluator did not know the results of the assessment with ImageJ and vice versa.
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* subject with mild to moderate myopia (-0.50 to -6.00 D) * age between 18-45 years old * subject who refuse refractive correction with glasses or surgery * patient with astigmatism refractive error no more than -1 Diopter
Exclusion criteria
* subject with previous intraocular surgery * subject who is wearing SCL continuously * subject with history of dry eyes, uveitis, glaucoma, or corneal and conjunctival disorders * subject with history of allergic reaction to contact lens material or lens wetting solution used in this study * subject with ongoing eye drop treatment * female subject with ongoing pregnancy or on breastfeeding * subject with too improper lens fitting * subject who work around exposure of chemical substance, smoke, hazardous gas, or fire sparks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Efron degree system for hyperemia degree | on day 0 (before using SCL), day 7, and day 14 | Hyperemia grade based on Efron degree system, identified by percentage of hyperemia on the bulbar dan limbal conjunctiva * Normal * Trace * Mild * Moderate * Severe |
| Image J analysis of hyperemia degree | on day 0 (before using SCL), day 7, and day 14 | Vascular density (%area) and Vascular diameter (μm ) |
Countries
Indonesia
Outcome results
None listed