Crohn Disease (CD), IBD (Inflammatory Bowel Disease), Ulcerative Colitis (UC)
Conditions
Keywords
IBD, ulcerative colitis, Crohn's disease, nutritional intervention
Brief summary
The goal of this clinical trial is to increase the knowledge on what type of diet affects inflammation and how to better convay that information in patients with inflammatory bowel disease (IBD) and decrease selective eating in patients with IBD. The main questions it aims to answer are: * will the use of calprotectin as a control for changes in inflammation decrease selective food choices? * will the use of a digital information tool increase quality of life (QoL) och decrease selctive eating patterns? * will a diet based on nordic food choices decrease inflammation and increase QoL? Researchers will compare with IBD-patients in ordinary care. Participants will eat a test diet during six weeks or go through a digital information tool.
Detailed description
Patients with inflammatory bowel disease attending the out-patient clinic at Skåne university hospital with calprotectin 200-600 will be invited to participate in this diet intervention study. They will be divided into four arms with 35 patients in each, normal diet, test diets or diet with digital information tool. The diet will be recorded at study start and end with a food diary for four days, as will health related quality of life. The patients clinical characteristics (demographics) and disease activity (diarrhoea frequency, blood in stools, abdominal pain, CRP and calprotectin) will be recorded. The patients clinical characteristics (demographics) and disease activity (diarrhoea frequency, blood in stools, abdominal pain, CRP and calprotectin) will be recorded.
Interventions
OTHERDiet
Healthy nordic based food
OTHEReducation
Digital information tool/education on food in inflammatory bowel disease (IBD)
Sponsors
Region Skane
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
Although the patients know that they will be given dietary advice they will not know what type of intervention the other group will be offered. Since dietary advice must be given by the investigators the study cannot be blinded to them.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Ulcerative colitis and Crohn's disease * Calprotectin 200-600
Exclusion criteria
* Non-active disease * solely procitis * Severe disease * past extensive bowel surgery * treatment with antibiotics (last month or present) * pregnancy * unability to understand spoken or written Swedish * Multimorbidity which aggrevate participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concentration of calproteictin | From enrollment until 6 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Four days registrered food intake | At beginning and after 6 week | Food intake will be registrered at beginning and after 6 week |
Countries
Sweden
Outcome results
None listed