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Lost in the Labyrinth: Predicting Central Neurological Causes of Vertigo Dizziness and Unsteadiness in the Emergency Department. A Multicentre Cross-sectional Observational Study

Lost in the Labyrinth: Predicting Central Neurological Causes of Vertigo Dizziness and Unsteadiness in the Emergency Department. A Multicentre Cross-sectional Observational Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07287891
Acronym
VERTIGO
Enrollment
825
Registered
2025-12-17
Start date
2024-01-26
Completion date
2027-02-26
Last updated
2025-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dizziness, ED With Vertigo, Unsteadiness

Brief summary

This study will assess the sensitivity and specificity of the bedside examination algorithm performed by ED physicians. Finally, it aims to identify predictors of a central cause of the symptoms. This will consequently reduce the rate of misdiagnosis as well as the costs and length of stay due to inappropriate neuroimaging.

Interventions

DIAGNOSTIC_TESTBedside examination of Vertigo

ED visit comprehensive of bedside examination of vertigo performed by trained EP or emergency medicine residents

Sponsors

Fondazione IRCCS Policlinico San Matteo di Pavia
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients presenting at the ED with vertigo, dizziness or unsteadiness * \>= 18 years of age * Patients able to give their consent

Exclusion criteria

* Patients with dementia * Bedridden patients (for causes other than the current symptoms) * Patients with obvious neurological findings presenting with vertigo but with suspected stroke at triage

Design outcomes

Primary

MeasureTime frame
The AUC of the bedside examination algorithm performed by ED physiciansup to 36 months

Secondary

MeasureTime frameDescription
identification of predictors of true positive patientsup to 36 monthsPredictors of true positive patients can help to stratify patients with vertigo for the risk of stroke.
evaluation of number of neuroimaging tests (TC and angio-TC) performed to patients with vertigo in the ED.tests performedup to 36 monthsto study the use of ED resources for these patients in terms of number of neuroimaging tests performed.

Countries

Italy

Contacts

Primary ContactMarco Bonzano, MD
m.bonzano@smatteo.pv.it+390382502039

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026