Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in HairTransplantation

Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in Hair Transplantation in Male Androgenic Alopecia

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07287579

Enrollment

Registered

2025-12-17

Start date

2026-01-31

Completion date

2027-12-31

Last updated

2025-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic Alopecia

Keywords

hair transplantation

Brief summary

* To compare the efficacy of platlet rich plasma and Nanofat injection as adjuvant therapies with FUE hair transplantation in improving graft survival rate, * To measure hair density and thickness postoperatively using dermoscopy or trichoscopy. * To evaluate patient satisfaction and photographic assessment by blinded evaluators. * To assess any adverse effects or complications related to each modality

Detailed description

* Ideal candidates for hair transplantation typically present with a clear, stable pattern of hair loss, characterized by at least 50% thinning or balding in 1 or more areas. The scalp must be healthy, with donor hair of good quality and quantity. Patients must have realistic expectations and be free of medical conditions that compromise surgical outcomes. The safe donor zone is located in the mid-occipital region between the upper and lower occipital protuberances, typically containing 65 to 85 follicular units/cm² * Intra-operative injection of PRP is beneficial in giving faster density, reducing the catagen loss of transplanted hair, early recovery of the skin, the faster appearance of new anagen hair in FUE hair transplantation. * This study compares the effects of PRP and Nano fat as adjuvants in Androgenic alopecia patients undergoing FUE hair transplantation. * Nanofat contain stem cells supposed to improve the results of FUE hair transplantation , but the question that we hope to answer at the end of our study which one we recommend as an adjuvant therapy PRP or Nano fat?

Interventions

PROCEDUREhair transplantation

we compare the effect of nanofat injection and platelet rich plasma in hair transplantation in male androgenic alopecia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* 1\. Male patients with stable androgenic alopecia more than 2 years. 2. Age 20-50 years 3. No recent medical hair loss treatments.

Exclusion criteria

* 1\. Active scalp infections or scarring alopecia. 2. Systemic diseases affecting wound healing. 3. Platelet disorders or anticoagulant use. 4. Smoking or heavy alcohol intake

Design outcomes

Primary

Measure	Time frame	Description
• To measure hair density using dermoscopy.	• All patients will be followed up about 6-12 months postoperative.	To measure how many hair follicles in each cubic centimetre

Contacts

Primary Contactshenouda Faiez, AL

shenoda011111@med.sohag.edu.eg0201285122844

Backup Contactmostafa haredy, MD

mostafaharedy84@gmail.com0201095159392

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026