Fatty Liver in Long Standing Cholecystectomy

Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patiens

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07284004

Acronym

MAFLD-Chole St

Enrollment

100

Registered

2025-12-16

Start date

2025-12-30

Completion date

2026-12-30

Last updated

2025-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)-Post-cholecystectomy Metabolic Changes -Hepatic Steatosis

Brief summary

This observational study aims to evaluate the association between long-term cholecystectomy and the development of metabolic dysfunction-associated fatty liver disease (MAFLD) in adult patients. The study will assess the prevalence and severity of hepatic steatosis in individuals who underwent cholecystectomy several years earlier and compare clinical, metabolic, and biochemical parameters to identify potential risk factors. The goal is to determine whether cholecystectomy contributes to metabolic alterations that increase the likelihood of MAFLD in the long term.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Exclusion criteria

1. Patients less than 18 years old. 2. Body mass index (BMI) ≤ 25 kg/m2 3. Patients with chronic renal failure. 4. Patients with liver cirrhosis. 5. Patients with acute liver dysfunction. 6. Breast feeding and pregnancy. 7. patients have done cholecystectomy less than 5 years ago.

Design outcomes

Primary

Measure	Time frame
Incidence and severity of metabolic dysfunction-associated fatty liver disease (MAFLD) in patients after long term follow up post cholecystectomy	5 years post-cholecystectomy

Secondary

Measure	Time frame
Changes in serum level of ALT in post-cholecystectomy patients	Annually for 5 years

Contacts

Primary ContactYasmeen Ahmed Farrag

yasmeen_ahmed_post@med.sohag.edu.eg201027291125

Outcome results