Postoperative Nausea and Vomiting, Total Joint Replacement Surgery
Conditions
Keywords
Aromatherapy, PONV
Brief summary
This study investigates the effectiveness of aromatherapy in reducing postoperative nausea and vomiting (PONV) among patients undergoing total joint replacement surgery, as these complications can lead to patient discomfort and prolonged recovery. It is designed as a randomized controlled trial involving 159 participants, who will be divided into three groups: an intervention group receiving aromatherapy patches (lavender-sandalwood or orange-ginger) plus standard care, a placebo group with a placebo patch plus standard care, and a control group receiving standard care alone. PONV will be measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR) at baseline, 30 minutes after the intervention, and every 12 hours post-surgery. Additionally, patient satisfaction will be assessed through a 5-point Likert scale survey. The primary outcome of the study is the evaluation of RINVR scores, while the secondary outcome focuses on patient satisfaction levels. Data will be statistically analyzed using two-way ANOVA for repeated measures, with a significance level defined as p \< 0.05. The study aims to determine the viability of aromatherapy as a complementary treatment for PONV, potentially improving postoperative care, enhancing patient satisfaction, and offering a cost-effective alternative to conventional anti emetic treatments if proven effective.
Interventions
OTHERAromatherapy patches
Applying aromatherapy patch served as intervention part in addition to standard care. Aromatherapy patch will be attached to the inner side of of the patient's top covered by a plain gauze with micro-pore tape.
OTHERPlacebo Patches
On top of standard care. Placebo patch, which looks like the aromatherapy patch but contains no element of any essential oil, will be attached to the inner side of of the patient's top covered by a plain gauze with micro-pore tape.
DRUGControl (Standard treatment)
Prescribed antiemetic treatment
Sponsors
Queen Elizabeth Hospital, Hong Kong
Hong Kong Buddhist Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
After completion of written informed consent, participants would be randomly assigned to one of three groups (Intervention, Placebo, Control) by a designated clerical staff according to a blocked randomization list. Outcome assessors were independent, not knowing information regarding condition or grouping of participants.
Intervention model description
Paralleled Randomized Controlled Trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults aged 18 or above * Patients scheduled for total joint replacement surgery at the HKBH
Exclusion criteria
* Cognitive impairments * Allergy to lavender, orange, ginger, or sandalwood * Allergy to micro-pore tape * Allergy to opioid medication * Undergoing other therapeutic treatment for PONV control, except prescribed medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Nausea and Vomiting | Through study completion, an average of 24 hours at 4 timepoints: T0 (baseline at PACU), T1 (up to 30 minutes from applying intervention to reassessment at PACU), T2 (up to 12-hour post-intervention in ward), T3 (up to 24-hour post-intervention in ward). | as measured by Rhodes Index of Nausea, Vomiting, and Retching, which consists of 8-item 4-point Likert-scales for nausea, vomiting, and retching symptoms with a total score ranging from 0 to 32 for each time point. The higher scores indicate the higher severity of nausea, vomiting, and retching experienced by the patient. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient Satisfaction | Through study completion, an average of 24 hours at 4 timepoints: T0 (baseline at PACU), T1 (up to 30 minutes from applying intervention to reassessment at PACU), T2 (up to 12-hour post-intervention in ward), T3 (up to 24-hour post-intervention in ward). | Use of patient satisfaction survey which consists of 2-item 5-point Likert scales to address the extent to which intervention could be effective in discomfort relief and control perceived by patients. The total score of the survey ranged from 2 to 10; the higher the score the more likely patients showed agreement on treatment effectiveness in discomfort relief and control. |
Countries
Hong Kong
Contacts
Primary ContactChoi Wan CHAN, APN (NURSING)
Backup ContactVictor CHEUNG, EOII(MDSSC)
Outcome results
None listed