TVS, SHG, and MRI in Uterine Niche

Comparative Assessment of Transvaginal Ultrasound, Hysterosonography, and MRI in Uterine Niche

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07279181

Enrollment

Registered

2025-12-12

Start date

2024-06-01

Completion date

2025-02-28

Last updated

2026-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Niche

Keywords

Uterine niche, MRI, Ultrasound, Hysterosonography

Brief summary

Uterine niche is a defect formed by poor healing of the lower uterine myometrium after cesarean section, defined as a depression of at least 2mm in the uterine myometrium at the cesarean scar; it is associated with gynecological symptoms and even life-threatening pregnancy complications, so accurate imaging evaluation is crucial for diagnosis, symptom grading, and treatment planning. Currently, transvaginal ultrasound (TVS), saline hysterosonography (SHG), and magnetic resonance imaging (MRI) are commonly used for evaluation, but there are controversies about the consistency of their measurements and repeatability of results. This observational study, conducted at the International Peace Maternity and Child Health Hospital affiliated with Shanghai Jiao Tong University School of Medicine, included women diagnosed with uterine niche.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Women (18-45 years) diagnosed with CSD at our center. * Women having postmenstrual spotting after CS * Signed informed consent.

Exclusion criteria

* Women who has a positive urine pregnancy test. * Presence of an intrauterine device. * With poor image quality from image will be excluded. * Refuse to participate in this study.

Design outcomes

Primary

Measure	Time frame	Description
Detection rates of niches	Periprocedural	Detection rates of niches

Secondary

Measure	Time frame	Description
Residual myometrial thickness	Periprocedural	Residual myometrial thickness of niches measured by TVS, SHG and MRI
The differences in the detection of abnormal structures	Periprocedural	The differences in the detection of abnormal structures

Countries

China

Contacts

STUDY_CHAIRJian Zhang

The International Peace Maternity & Child Health Hospital

Outcome results