Caries Active, Tooth Decay, Tooth Loss / Rehabilitation
Conditions
Keywords
tooth loss, decay, caries, biomaterials
Brief summary
Understanding, through accurate and reliable volumetric analysis, how the biomaterial (LPRF) and the thickness of the vestibular bone plate influence changes in bone volume after extraction, is essential for making clinical decisions that impact implant-supported rehabilitation.
Interventions
teeth to either the control group (coagulant-filled alveoli) or the test group (alveoli filled with platelet-rich fibrin and LPRF leukocytes)
Sponsors
University of Guarulhos
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
21 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
This prospective clinical study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki and received approval from the Research Ethics Committee of Guarulhos University, São Paulo, Brazil (CEP-UnG #. 515.153). Thirty-nine patients (24 women and 15 men), aged between 22 and 80 years, who were in overall good health, non-diabetic, periodontally healthy, non-smokers, free of blood dyscrasias, not pregnant or lactating, and requiring extraction of non-contiguous, compromised teeth due to root fractures, caries, unsuccessful endodontic treatment, root resorption, or orthodontic reasons, were enrolled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bone volume after 16 weeks | 16 weeks |
| aveolar bone contraction | 4 months |
Outcome results
None listed