Atrial Fibrillation (AF)
Conditions
Brief summary
To evaluate the feasibility of specific echocardiographic parameters as criteria for AF screening and to determine the AF detection yield of scheduled extended ECG monitoring compared to contemporary care.
Interventions
DIAGNOSTIC_TESTstudy arm
Scheduled cardiac rhythm monitoring every 3 months using extended continuous ECG monitoring
Sponsors
Tze-Fan Chao
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
patients who met any of the following criteria 1. LAE: defined as LAD ≥ 45 mm or LAVI \> 34 ml/m2; 2. LVH: defined as LV septal or posterior wall thickness ≥ 15 mm; 3. E/e' \> 14; 4. grade II or III diastolic dysfunction; 5. VHD; 6. HF: defined as LVEF \< 40% or LVEF ≥40% with clinical presentation compatible with Framingham criteria, New York Heart Association functional classification II-IV, and N-terminal pro-B type natriuretic peptide (NT-proBNP) \> 125 pg/ml.
Exclusion criteria
* Patients with a history of AF or atrial flutter, congenital heart disease, acute coronary syndrome undergoing urgent percutaneous coronary intervention within 3 months, uncontrolled hyperthyroidism, end-stage renal disease, unstable hemodynamic status or any known major comorbidities or medical conditions with expected life expectancy less than 1 year are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the detection of AF either by 12-lead ECG or any episodes of AF lasting ≥ 30 seconds by the single-lead ECG or 7-day continuous recording. | 2 years |
Countries
Taiwan
Contacts
Primary ContactTze-Fan Chao, PhD
Outcome results
None listed