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The Safe Early Mobilization on CABG

The Effect of the Safe Early Mobilization Protocol Developed for Patients Underwent Coronary Artery Bypass Graft Surgery on Patient Outcomes

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07276971
Enrollment
60
Registered
2025-12-11
Start date
2023-10-01
Completion date
2023-12-29
Last updated
2026-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Bypass Graft, Nursing

Keywords

Coronary artery bypass graft, Cardiovascular nursing, Early mobilization protocol, Patient outcomes

Brief summary

Aim: This study aimed to evaluate the effect of a Safe Early Mobilization Protocol (SEMP) developed for patients undergoing coronary artery bypass graft (CABG) surgery on patient outcomes. Design: A single-center, parallel-group, randomized controlled trial. Methods: The study was conducted with 60 patients in 2023. The intervention group received a Safe Early Mobilization Protocol including bedside elevation, deep breathing and coughing exercises, sitting upright in bed, sitting on the edge of the bed, standing, ambulation, and sitting in a bedside chair from the day of surgery until the fourth postoperative day. The control group received routine mobilization care. Respiratory parameters, orthostatic hypotension (OH), orthostatic intolerance (OI), mobilization distance, anxiety level, and hospital stay were evaluated.

Interventions

OTHERThe safe early mobilization protocol

This protocol was developed to guide the early postoperative mobilization of patients undergoing coronary artery bypass graft surgery, covering the period from the day of surgery to the fourth postoperative day. Prior to mobilization, patients are evaluated using a checklist ensuring physical and environmental safety. On the day of surgery, following extubation by the responsible physician, six stages are applied: bed head elevation, deep breathing exercises, incentive spirometry, passive range of motion (ROM) exercises, sitting upright (90°), and sitting on the edge of the bed. On postoperative days 1-3, standing at the bedside, ambulation, and sitting on a chair are added. Target walking distances are 100-150 m on day 1, 200-250 m on day 2, and 300-350 m on day 3. Distances are measured by the researcher using a meter. The protocol concludes on the 4th postoperative day when the patient can ambulate independently.

OTHERControl Group

Patients in the control group were informed about the current mobilization practices applied in the clinic before surgery. The morning after the surgery (the first day after the surgery), the patient is first seated in the bed, and in the second stage, he is made to sit on the edge of the bed with his feet touching the floor and is observed. In the third stage, the patient stands in an upright position and if there is no dizziness or blackout, the patient is seated on a chair next to the bed. The duration of sitting in the chair is determined depending on the general condition of the patient (pain, dizziness, blackout, nausea). On the 2nd and 3rd postoperative day, patients were contacted by nurses and care support staff while they had a chest tube; Then, the patient is mobilized only with his/her relative. There is no standard practice regarding how long patients should be mobilized during the day.

Sponsors

Hulya BULUT
Lead SponsorOTHER
Lokman Hekim University
CollaboratorOTHER_GOV
Ankara Guven Hospital
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Hemodynamic stability, defined as: Resting heart rate \<110/min Mean arterial pressure between 60-110 mmHg Oxygen saturation (SpO₂) \>88% Receiving dopamine infusion ≤5 mcg/kg/min at the time of enrollment No auditory, speech, or visual impairments No neurological contraindications (e.g., cerebrovascular accident \[CVA\], ataxia, multiple sclerosis \[MS\]) No orthopedic contraindications that prevent mobilization (e.g., fractures or sequelae) Provided informed consent to participate in the study Age ≥18 years Able to speak Turkish Literate patients

Exclusion criteria

Requirement for intra-aortic balloon pump (IABP) support Postoperative cerebrovascular events High-dose inotropic drug infusion in the early postoperative period: Dopamine ≥10 mcg/kg/min Norepinephrine ≥0.5 mcg/kg/min Concurrent dopamine and norepinephrine infusion Severe arrhythmias preventing mobilization, including: Sinus tachycardia ≥120/min Rapid atrial fibrillation Ventricular tachycardia Ventricular fibrillation Advanced chronic obstructive pulmonary disease (COPD) or bronchiectasis Diagnosed anxiety disorders

Design outcomes

Primary

MeasureTime frameDescription
Distance walked during postoperative mobilizationPostoperative Days 1, 2, and 3.Distance walked (meters) during routine postoperative mobilization in the hospital corridor, measured using a standardized corridor distance measurement protocol. Greater distances indicate better postoperative mobility.

Secondary

MeasureTime frameDescription
Number of Participants With Orthostatic HypotensionDaily postoperative measurements for up to 3 days.Orthostatic hypotension defined as a ≥20 mmHg decrease in systolic BP and/or ≥10 mmHg decrease in diastolic BP.
Number of Participants With Orthostatic IntoleranceDaily postoperative assessments for up to 3 days.Orthostatic intolerance defined as the presence of dizziness, nausea, weakness, blurred vision, or syncope.considered as OI.
Oxygen Saturation Level (%)Daily postoperative measurements for up to 3 days.Peripheral oxygen saturation (SpO₂) measured using pulse oximetry.
State Anxiety Scale ScorePostoperative day 1 and postoperative day 4.The State Anxiety Inventory (STAI-S) will be used (score range: 20-80; higher scores indicate worse anxiety).
Six-Minute Walk Test Distance (Meters)Postoperative day 4.Distance walked during the Six-Minute Walk Test (0-∞ meters; higher distance indicates better functional capacity).
Length of Hospital Stay (Days)From postoperative day 0 until hospital discharge (up to 30 days).Total duration of postoperative hospitalization, including ICU and ward stay.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 23, 2026