DIAGNOSTIC CONTRIBUTION OF EARLY ABDOMINAL ULTRASOUND IN THE SITUATION OF ACUTE ABDOMEN OF PREMATURE

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07275268

Acronym

EchoPrémA

Enrollment

100

Registered

2025-12-10

Start date

2025-12-31

Completion date

2028-06-30

Last updated

2025-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Abdomen in Children

Brief summary

This study will assess the diagnostic contribution of early abdominal ultrasound for acute abdomen in premature newborns. Early ultrasound assessment would provide diagnostic assistance, in conjunction with clinical examination and biological testing, in the three main clinical situations encountered with an acute abdomen in premature infants: enterocolitis (digestive translocation of a bacterium secondary to inflammation, local fragility of the digestive tract, associated ischemic phenomena), reflex ileus (decrease in intestinal peristalsis secondary to peritoneal reactivity following inflammatory phenomena) and digestive immaturity (expressed by bloating, regurgitation, absence of spontaneous transit, related to the degree of prematurity).

Interventions

PROCEDUREAbdominal Ultrasound

Abdominal Ultrasound

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

No minimum to 36 Weeks

Healthy volunteers

Inclusion criteria

Premature under 37 weeks of amenorrhea with an adverse event of special interest such as : * altered abdomen with bloating or presence of previsouly unknow marked collateral circulation, * absence of spontaneous transit (\> 48 hours), * episode of rectal bleeding, * repeated regurgitation/vomiting (during more than 50% of feedings), * prolonged fasting (\>12 hours), OR * increase in cardiorespiratory events on continuous monitoring associated with one of the elements listed above.

Exclusion criteria

* organic malformation detected during prenatal monitoring or discovered in the immediate postnatal period, * chromosomal abnormality detected during prenatal monitoring or discovered in the immediate postnatal period,- spontaneous perforation occurring during the first week of life.

Design outcomes

Primary

Measure	Time frame	Description
Presence or absence of echographic signs	Day 5	Presence of positive echographic signs such as: aeroportia, pneumatosis parietalis, pneumoperitoneum, bowel wall thickening, fluid effusion, distension of bowel loops, during the early echography for premature newborns with digestive symptomatology.

Contacts

Primary ContactMorgane VIDONI AGUILAR, Int

maguilarrubio@chu-besancon.fr0033 3 81 21 91 61

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026