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Effect of Manual Lymphatic Drainage on Muscle Fatigue in Female 11-a-side Football Players

Effect of Manual Lymphatic Drainage on Muscle Fatigue in Female 11-a-side Football Players

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07274033
Acronym
EDLMF11
Enrollment
11
Registered
2025-12-10
Start date
2025-11-17
Completion date
2026-06-30
Last updated
2026-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women

Keywords

Manual Lymphatic Drainage, Football, Women

Brief summary

This clinical trial investigates the effectiveness of manual lymphatic drainage (MLD) in accelerating recovery following induced fatigue in female football players. The study integrates objective performance measurements using linear encoders with anthropometric assessments and psychophysiological evaluations. It aims to quantify the impact of MLD on neuromuscular recovery, muscle edema, and perceived fatigue, considering sex-specific physiological factors and the influence of sleep and psychological stress. The findings will contribute to developing non-invasive, individualized recovery strategies to enhance performance and reduce injury risk in women's football.

Detailed description

This study aims to assess the effectiveness of manual lymphatic drainage (MLD) as a recovery strategy following induced fatigue in female football players. The intervention is applied immediately after a standardized fatigue protocol using a linear encoder to objectively measure performance decline. The study adopts a multidimensional approach, integrating biomechanical, physiological, and psychometric variables to evaluate recovery. Participants will undergo three experimental sessions involving a fatigue protocol followed by either MLD or control conditions. Performance will be assessed through guided machine squats, measuring the number of repetitions and time until a 20% velocity loss. Thigh circumference will be measured pre- and post-intervention to monitor fluid shifts and potential edema. Subjective recovery perception will be recorded, and emotional state will be evaluated using the Hospital Anxiety and Depression Scale (HADS). Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI) to explore its influence on fatigue and recovery response. This trial addresses the need for non-invasive, efficient recovery strategies tailored to female athletes, considering sex-specific physiological and psychological factors. The findings may contribute to optimizing post-exercise recovery protocols and reducing injury risk in women's football.

Interventions

OTHERManual lymphatic draige

This method, part of complex decongestive physiotherapy, involves gentle massage techniques that stimulate lymphatic circulation and venous return. MLD promotes lymph fluid mobilization, increases lymphangiomotor activity, and has positive effects on the immune system. Its application has shown to reduce limb edema, decrease muscle fatigue, and raise pain thresholds. Moreover, the gentle touch during MLD activates cutaneous receptors that influence the parasympathetic nervous system, producing physiological changes such as reduced heart rate, blood pressure modulation, and increased muscle strength.

Sponsors

Camilo Jose Cela University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Masking description

One of the members of the research team that will carry out the data analysis is not aware of the intervention that will be performed

Eligibility

Sex/Gender
FEMALE
Age
16 Years to 20 Years
Healthy volunteers
Yes

Inclusion criteria

* Female athletes actively participating in 11-a-side football, either federated or official team members. * Age ≥ 16 years to 20 years old. * Regular training (≥ 3 sessions per week) or active competition * No food intake within 3 hours prior to evaluation (to standardize the influence of digestion on performance). * No acute lower limb injury in the past 3 months. * Availability to attend all three study visits. * Signed informed consent; for participants under 18, parental consent is also required.

Exclusion criteria

* History of deep vein thrombosis * Decompensated heart failure * Active lower limb infection * Pregnancy * Recent lower limb surgery (\< 3 months), or any medical contraindication to receiving manual lymphatic drainage (MLD). * Failure to comply with the fasting requirement prior to performance testing.

Design outcomes

Primary

MeasureTime frameDescription
Number of repetitionsbaseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.Number of repetitions until 20% velocity loss: recorded via linear encoder during guided squat test.
Time to fatiguebaseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.Time to fatigue (seconds): total time from first repetition until velocity drops by 20%.
Velocity profilebaseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.average velocity per repetition, expressed in m/s.
Thigh circumference (cm)baseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.measured with a non-elastic tape at the midpoint between the anterior superior iliac spine and the upper border of the patella, in both legs, pre- and post-intervention.
Perceived fatiguebaseline; 5 minutes before and 5 moinutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.assessed using Borg CR-10 scale (0 = no fatigue, 10 = maximum fatigue).
Perceived pain (VAS)baseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.assessed using Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (maximum pain).
Perceived recovery (PRS)baseline; 5 minutes before and 5 minutes after the first procedure, 5 minutes before and 5 minutes after the second procedure, and 15 days after the procedure was completed.assessed using the Perceived Recovery Status Scale (PRS), ranging from 0 (no recovery) to 10 (full recovery).

Secondary

MeasureTime frameDescription
Sleep quality (PSQI)baseline, after the second procedure and 15 days after the procedure was completedassessed using the Pittsburgh Sleep Quality Index (PSQI), a 19-item questionnaire with scores ranging from 0 to 21 (higher scores indicate poorer sleep quality).
Emotional statebaseline, after the second procedure and 15 days after the procedure was completedassessed using the Hospital Anxiety and Depression Scale (HADS), comprising 14 items across anxiety and depression subscales (scores range from 0 to 21 per subscale).
Sociodemographic VariablesBaselineAge, Height, Body weight, Body mass Index
Dominant legBaselineself-reported (leg used to kick the ball).
Sports experience (years)baselinetotal years of systematic football practice.
Training frequency (sessions/week)baselineaverage number of sessions during the season.
Menstrual cycle phasebaseline, after the second procedure and 15 days after the procedure was completedself-reported, to control for physiological variations in fatigue and recovery.

Countries

Spain

Contacts

PRINCIPAL_INVESTIGATOREdurne Úbeda Docasar, Doctor

University Camilo José Cela

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 30, 2026