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The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.

Effect of Sugar-Free Chewing Gum Mastication on Fatigue of the Masticatory Muscles in Young Adults With and Without Temporomandibular Joint Disorders

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07273123
Enrollment
30
Registered
2025-12-09
Start date
2025-10-01
Completion date
2026-07-30
Last updated
2026-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular Joint Disorder

Brief summary

This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD). The study addresses two primary questions: How does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses. All participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.

Interventions

OTHERMastication of sugar-free chewing gum

The chewing task will last for a maximum of 18 minutes.

Sponsors

University of Milan
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
19 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

(both groups): * Age 19-35 years * Chewing-gum users, even occasional * Good general health * Good oral health Inclusion criteria (Healthy controls): \- no diagnosed temporomandibular joint disorders Inclusion criteria (study group) \- diagnosed temporomandibular joint disorders

Exclusion criteria

(both groups): * Non chewing gum users * History of neurological disorders * History of musculoskeletal diseases * History of facial or cervical injuries * Presence of cervical pain * Two or more missing teeth * Current treatment with fixed or removable orthodontic appliances * Active periodontal disease * Presence of cavitated carious lesions

Design outcomes

Primary

MeasureTime frame
Self-reported (subjective) fatigue after prolonged sugar-free chewing gum masticationThe whole session has a maximum duration of 18 minutes, assessments are done every 3 minutes

Secondary

MeasureTime frame
Changes of static and dynamic surface electromyography (sEMG) parameters after prolonged mastication of sugar-free chewing gumThe whole session has a maximum duration of 18 minutes, assessments are done every 3 minutes

Countries

Italy

Contacts

CONTACTAesha Allam, DDS
aesha.allam@unimi.it+39 3276218958

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 2, 2026