Nuclear Medicine
Conditions
Keywords
SPECT/CT
Brief summary
The goal of this pilot study is to evaluate capabilities of the StarGuide NextGen SPECT/CT system to inform future clinical use of this technology.
Detailed description
The StarGuide NextGen system is expected to offer superior image quality and faster scanning times relative to our standard clinical SPECT systems. However, the optimal scanning parameters for StarGuide NextGen are yet undetermined. This research study is necessary to assess the feasibility of patient scanning on this system and to refine the parameters in preparation for future clinical use. The study is also important to inform whether and to what degree the StarGuide NextGen can improve image quality over standard dual-head SPECT/CT scanners for a variety of common nuclear medicine exams.
Interventions
DEVICEStarGuide NextGen SPECT/CT system
Within 1 hour of the participant receiving a scheduled clinical nuclear medicine procedure, a research scan will be performed with the StarGuide NextGen SPECT/CT system for detection of radiopharmaceutical uptake in the patient body. The total time for the scan will range from 20 - 60 minutes.
Sponsors
Mayo Clinic
GE Healthcare
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Scheduled for clinical administration of a radiopharmaceutical for a clinical nuclear medicine imaging test or radiopharmaceutical therapy * Able to provide consent for study participation StarGuide NextGen Evaluation
Exclusion criteria
* Unable to comply with physical requirements for lying supine on the StarGuide NextGen patient bed * Pregnant. (Note that pregnancy status will be established via clinical standard of care for the clinical nuclear medicine test prior to administration of radiopharmaceutical.) * Unable to provide consent for study participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic image quality | 1 year | Diagnostic image quality of StarGuide NextGen and clinical scans, will be assessed by study radiologists using a Likert scale of 1-5, where 1 = Non-diagnostic; 2 = Poor; 3 = Adequate; 4 = Good; and 5 = Excellent. For future clinical use, acceptable image quality will be considered as having scores of 4 or 5. |
Secondary
| Measure | Time frame |
|---|---|
| Count sensitivity | 1 year |
| Lesion contrast | 1 year |
| Signal-to-noise ratio (SNR) | 1 year |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORCarrie B. Hruska, PhD
Mayo Clinic
Outcome results
None listed