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Deep Breathing Combined With Core Stability Exercises in the Treatment of Patients With Ankylosing Spondylitis

The Effect of Deep Breathing Added to Core Stability Exercises in the Treatment of Patients With Ankylosing Spondylitis: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07262294
Acronym
RCT
Enrollment
30
Registered
2025-12-03
Start date
2026-02-01
Completion date
2026-12-30
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis (AS)

Brief summary

Exercise may be considered the gold standard for the management of mechanical and functional symptoms associated with patients having AS and they are considered as a safe and effective treatment for improving strength, spinal mobility, and physical fitness in general. However, there were no definite types or doses recommended over others. Additionally, poor posture is one of the consequences of AS due to pain, loss of flexibility, and muscular weakness which may also affect respiratory function. This faulty mechanical posture of the thoracic and cervical spine may affect the pulmonary function of these patients. Therefore, the purpose of the current study is to investigate the efficacy of deep breathing exercises added to core stability exercises in the treatment of patients suffering from AS.

Detailed description

The management of AS typically involves a multidisciplinary approach which includes both medical and physical therapy approaches, concerning the medical treatment, NSAIDs are widely used for pain relief and inflammation control in AS patients and were recommended for the management of patients having AS. The efficacy of NSAIDs has been well-documented in research studies, Disease-modifying antirheumatic Drugs (DMARDs), including sulfasalazine and methotrexate, play a crucial role in suppressing inflammation and preventing joint damage in AS patients, or biologics, such as tumor necrosis factor (TNF) inhibitors (adalimumab, etanercept, infliximab), have transformed AS treatment by specifically targeting inflammatory pathways and significantly improving symptoms and function. Respecting the physical therapy approach plays a crucial role aims to maintaining and improving mobility, reducing pain, enhancing overall function, correcting mal-positioning, and improving patients' psychological status in patients with ankylosing spondylitis. It usually includes a combination of exercises such as Range of Motion (ROM) exercises, strengthening exercises, Cardiovascular exercises, postural training, patient education, assistive devices, Adaptations, and monitoring. Different types of exercises have been studied for managing patients having AS, however, no specific type has been recommended over others. Additionally, up to our knowledge, there were no studies has addressed the respiratory function that may be affected with patients having AS either from postural abnormalities, lack of spinal flexibility, or generalized functional limitations. Therefore, the current study aims to evaluate if deep breathing exercises as a complementary intervention would be of some value when added to core stability exercises for patients suffering from AS.

Interventions

OTHERExercises

Exercises

Sponsors

Beni-Suef University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Masking description

Double blind

Intervention model description

Parallel Assignment

Eligibility

Sex/Gender
ALL
Age
25 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* Receiving the same medical treatment * Age range between 20 and 45 years * Includes both male and female patients * Diagnosed with stable ankylosing spondylitis (AS) for at least 3 months * Not engaged in any other rehabilitation programs within the last 6 months

Exclusion criteria

* Presence of other systemic or neurological disorders * Any change in medication within the last 6 months

Design outcomes

Primary

MeasureTime frameDescription
Respiratory functionPatients will be examined after 4 to 6 weeksForced vital capacity (FVC) which measure lung volume, and it reflects the capacity of the lung. Forced expiratory volume in 1 second (FEV1) which measure lung velocity, and it evaluate the presence of airway obstruction. FEV1/FVC it the index that differentiate between obstructive and restrictive lung disease.

Secondary

MeasureTime frameDescription
Functional exercise capacityPatients will be examined after 4 to 6 weeksThe physical functional performance will be assessed by a six-minute walk test (6 MWT)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026